Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP7 | P09237 | 3/20 | 0.53 |
| ▸ | MMP10 | P09238 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443795 | 0.89 | MMP9 (0.54) | MMP9MMP7MMP10MMP2MMP1 | |
| SCHEMBL5180159 | 0.89 | MMP9 (0.54) | MMP9MMP7MMP10MMP2MMP1 | |
| SCHEMBL1443796 | 0.89 | MMP9 (0.54) | MMP9MMP7MMP10MMP2MMP1 | |
| SCHEMBL4927384 | 0.83 | MMP7 (0.74) | MMP9MMP7MMP10MMP2MMP1 | |
| SCHEMBL4927389 | 0.83 | MMP7 (0.74) | MMP9MMP7MMP10MMP2MMP1 | |
| SCHEMBL4921444 | 0.81 | MMP13 (0.58) | MMP9MMP7MMP10MMP2MMP1 | |
| SCHEMBL4921436 | 0.81 | MMP13 (0.58) | MMP9MMP7MMP10MMP2MMP1 | |
| SCHEMBL4926651 | 0.80 | MMP1 (0.56) | MMP9MMP7MMP2MMP1MMP14 | |
| SCHEMBL5094030 | 0.80 | MMP1 (0.56) | MMP9MMP7MMP2MMP1MMP14 | |
| SCHEMBL7473654 | 0.80 | MMP2 (0.57) | MMP9MMP7MMP10MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796681-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | Genmedica Therapeutics SL (ES) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006013209-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | GENMEDICA THERAPEUTICS SL (ES) | 2006-02-09 | — | — | WO | disclosed |