Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 6/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941247 | 0.87 | XDH (0.41) | XDHPTPRCPTPN1MEN1LMNA | |
| SCHEMBL2474403 | 0.80 | PDE3B (0.45) | XDHPTPRCPTPN1MEN1LMNA | |
| SCHEMBL2476180 | 0.80 | TNKS (0.46) | XDHPTPRCPTPN1MEN1LMNA | |
| SCHEMBL3161240 | 0.80 | XDH (0.41) | XDHPTPRCPTPN1MEN1LMNA | |
| SCHEMBL2477166 | 0.80 | PTGER1 (0.47) | XDHPTPRCPTPN1MEN1LMNA | |
| SCHEMBL1129691 | 0.78 | XDH (0.51) | XDHPTPRCMEN1LMNATHRB | |
| SCHEMBL23480395 | 0.77 | ALOX5AP (0.42) | PTPRCPTPN1MEN1LMNATHRB | |
| SCHEMBL1631167 | 0.77 | PTGS2 (0.54) | XDHMEN1LMNATHRBBLM | |
| SCHEMBL28743346 | 0.76 | XDH (0.38) | XDHPTPRCPTPN1MEN1LMNA | |
| SCHEMBL2562357 | 0.76 | ACMSD (0.50) | PTPN1MEN1LMNAKMT2AERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446210-B2 | Factor Xa compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-11-04 | — | — | US | disclosed |
| EP-1807082-A2 | FACTOR XA COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | disclosed |
| US-20060199809-A1 | Factor Xa compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-09-07 | — | — | US | disclosed |
| WO-2006047415-A2 | FACTOR XA COMPOUNDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199809-A1 | Factor Xa compounds | F11, F12, F5 | KIF11 4112/4885XDH 40/4885PTPRC 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.