Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510474 | 0.83 | SRC (0.44) | AKR1C3AKR1C2ALDH1A1MEN1KMT2A | |
| SCHEMBL16744658 | 0.80 | HTT (0.39) | AKR1C3AKR1C2CYP2C9CYP2C19MEN1 | |
| SCHEMBL8169224 | 0.80 | HTT (0.39) | AKR1C3AKR1C2CYP2C9CYP2C19MEN1 | |
| SCHEMBL1357313 | 0.80 | HTT (0.39) | AKR1C3AKR1C2CYP2C9CYP2C19MEN1 | |
| SCHEMBL3171360 | 0.80 | GRM1 (0.38) | AKR1C3AKR1C2MEN1KMT2AGRM1 | |
| SCHEMBL29009754 | 0.78 | AKR1C3 (0.45) | AKR1C3AKR1C2MEN1KMT2AGRM1 | |
| SCHEMBL27912616 | 0.76 | SMN1; SMN2 (0.48) | AKR1C3AKR1C2MEN1KMT2AGRM1 | |
| SCHEMBL6833039 | 0.76 | MRGPRX4 (0.40) | AKR1C3AKR1C2MEN1KMT2AGRM1 | |
| SCHEMBL510121 | 0.76 | SRC (0.48) | AKR1C3AKR1C2ALDH1A1MEN1KMT2A | |
| SCHEMBL1928791 | 0.75 | ACP3 (0.43) | AKR1C3AKR1C2ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673818-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSCHAFT (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8334300-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSHAFT (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| US-8193120-B2 | C2-phenyl-substituted cyclic ketonols | BAYER AKTIENGESELLSCHAFT (DE) | 2012-06-05 | — | — | US | disclosed |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20110183849-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110143943-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2011-06-16 | — | — | US | disclosed |
| US-7915282-B2 | Preparation by intramolecular cyclization | BAYER AKTIENGESELLSCHAFT (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20100298142-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2187745-A2 | HERBICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009035151-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| US-20030216260-A1 | C2-phenyl-substituted cyclic keto-enols used as pesticides and herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | C5, C1S, WEE1 | AKR1C3 107/4885AKR1C2 534/4885CRHBP 2421/4885 |
| US-20030216260-A1 | C2-phenyl-substituted cyclic keto-enols used as pesticides and herbicides | PDHX, AKR1C3, AKR1A1 | AKR1C3 2/4885AKR1C2 6/4885CRHBP 3137/4885 |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | CHRM2, CHRM1, WEE1 | AKR1C3 599/4885AKR1C2 871/4885CRHBP 4306/4885 |
| US-20110143943-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, PDHX, AKR1C2 | AKR1C3 1/4885AKR1C2 3/4885CRHBP 3112/4885 |
| US-20110183849-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, PDHX, AKR1C2 | AKR1C3 1/4885AKR1C2 3/4885CRHBP 3112/4885 |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | WEE1, WEE2, H1-3 | AKR1C3 594/4885AKR1C2 1163/4885CRHBP 4314/4885 |
| US-20100298142-A1 | HERBICIDAL COMPOSITION | CYP2W1, WEE2, CYP2J2 | AKR1C3 436/4885AKR1C2 541/4885CRHBP 4517/4885 |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, AKR1C4, AKR1C2 | AKR1C3 1/4885AKR1C2 3/4885CRHBP 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.