Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207353 | 0.86 | SRC (0.46) | SRCTAS1R3TAS1R1TAS1R2CACNA1G | |
| SCHEMBL510121 | 0.86 | SRC (0.48) | SRCAKR1C3AKR1C2TAS1R3TAS1R1 | |
| SCHEMBL3382824 | 0.84 | SRC (0.43) | SRCCACNA1GCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL5156728 | 0.83 | PDE5A (0.41) | SRCCACNA1GCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL16744658 | 0.83 | HTT (0.39) | AKR1C3AKR1C2MEN1KMT2AGRM1 | |
| SCHEMBL19200334 | 0.83 | AKR1C3 (0.50) | SRCAKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL509516 | 0.83 | AKR1C3 (0.43) | AKR1C3AKR1C2MEN1KMT2AGRM1 | |
| SCHEMBL3171360 | 0.83 | GRM1 (0.38) | SRCAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL16672638 | 0.83 | SMN1; SMN2 (0.49) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL8169224 | 0.83 | HTT (0.39) | AKR1C3AKR1C2MEN1KMT2AGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | claimed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | claimed |
| US-8962625-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8541414-B2 | Pyridazinone compound and use thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-24 | — | — | US | disclosed |
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| US-8067458-B2 | Alkoxyalkyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20100298142-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2218330-A1 | Process for the preparation of 2-ethyl-4,6-dimethylphenyl acetic acid by reacting 2-ethyl-4,6-dimethylbromobenzene with tert.-butylacetate | Bayer CropScience AG (DE) | 2010-08-18 | — | — | EP | disclosed |
| EP-1996557-B1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2010-03-03 | — | — | EP | disclosed |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-09-24 | — | — | US | disclosed |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| EP-1996557-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | Sumitomo Chemical Company, Limited (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007119434-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-25 | — | — | WO | disclosed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
| EP-1296918-A2 | DIMETHYLBENZENE DERIVATIVES | Cognis Deutschland GmbH & Co. KG (DE) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002494-A2 | DIMETHYLBENZENE DERIVATIVES AND THEIR USE AS ODORIFEROUS SUBSTANCES | COGNIS DEUTSCHLAND GMBH & CO. KG (DE) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | C5, C1S, WEE1 | SRC 4045/4885AKR1C3 107/4885AKR1C2 534/4885 |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | DDT, DDC, DAO | SRC 3316/4885AKR1C3 1506/4885AKR1C2 1407/4885 |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | CHRM2, CHRM1, WEE1 | SRC 4243/4885AKR1C3 599/4885AKR1C2 871/4885 |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | WEE1, WEE2, H1-3 | SRC 3342/4885AKR1C3 594/4885AKR1C2 1163/4885 |
| US-20090239906-A1 | ALKOXYALKYL-SUBSTITUTED CYCLIC KETOENOLS | DDT, EBP, TET1 | SRC 2220/4885AKR1C3 27/4885AKR1C2 30/4885 |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | PDXK, DDT, PLPBP | SRC 4272/4885AKR1C3 742/4885AKR1C2 687/4885 |
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | DDT, DDC, DAO | SRC 3316/4885AKR1C3 1506/4885AKR1C2 1407/4885 |
| US-20100298142-A1 | HERBICIDAL COMPOSITION | CYP2W1, WEE2, CYP2J2 | SRC 4621/4885AKR1C3 436/4885AKR1C2 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.