Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095308 | 1.00 | USP2 (0.38) | USP2VDRSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL5102184 | 0.85 | CHRM2 (0.34) | USP2VDRALDH1A1MAPTCHRM2 | |
| SCHEMBL5102182 | 0.85 | CHRM2 (0.34) | USP2VDRALDH1A1MAPTCHRM2 | |
| SCHEMBL4606719 | 0.85 | CHRM2 (0.40) | USP2VDRSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL4607441 | 0.85 | CHRM2 (0.40) | USP2VDRSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL4606721 | 0.85 | CHRM2 (0.40) | USP2VDRSLC6A12SLC6A11SLC6A13 | |
| SCHEMBL18844170 | 0.83 | ALDH1A1 (0.33) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL25069171 | 0.82 | BRD4 (0.38) | USP2VDRALDH1A1MAPTCHRM2 | |
| SCHEMBL20099504 | 0.81 | SLC6A1 (0.33) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL606928 | 0.79 | SLC6A12 (0.37) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449461-B2 | Benzathiazol-acetamides | HOFFMANN-LA ROCHE INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20060019950-A1 | Benzathiazol-acetamides | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019950-A1 | Benzathiazol-acetamides | CHRNA2, CHRNA10, CHRNA5 | USP2 3034/4885VDR 3629/4885SLC6A12 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.