Biphenyl

Biphenyl

SCHEMBL5095997

C=CCOc1ccc(C(=O)O)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PKM P14618 1/20 0.57
NR4A2 P43354 2/20 0.54
NR4A1 P22736 1/20 0.54
NR4A3 Q92570 1/20 0.54
CHRNB2 P17787 1/20 0.53
CHRNB4 P30926 1/20 0.53
CHRNA3 P32297 1/20 0.53
CHRNA4 P43681 1/20 0.53
FFAR1 O14842 1/20 0.53
HTT P42858 1/20 0.51
SRD5A2 P31213 1/20 0.50
BACE1 P56817 1/20 0.50
NPC1 O15118 2/20 0.49
MAPT P10636 2/20 0.49
RAB9A P51151 2/20 0.49
POLB P06746 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
PLA2G4A P47712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL9750866 0.95 FFAR1 (0.55) ALDH1A1L3MBTL1PKMNR4A2NR4A1
SCHEMBL5840304 0.93 ALDH1A1 (0.61) ALDH1A1L3MBTL1PKMNR4A2NR4A1
Benzene SCHEMBL28158854 0.93 ALDH1A1 (0.65) ALDH1A1L3MBTL1PKMNR4A2NR4A1
Hydrochloric Acid SCHEMBL8986262 0.92 ALDH1A1 (0.59) ALDH1A1L3MBTL1PKMNR4A2NR4A1
SCHEMBL1489146 0.92 ALDH1A1 (0.67) ALDH1A1L3MBTL1PKMNR4A2NR4A1
Hydrochloric Acid SCHEMBL711176 0.90 ALDH1A1 (0.65) ALDH1A1L3MBTL1PKMNR4A2NR4A1
SCHEMBL5090338 0.89 MMP2 (0.50) ALDH1A1L3MBTL1PKMNR4A2NR4A1
SCHEMBL9122915 0.87 POLB (0.55) ALDH1A1L3MBTL1PKMSRD5A2POLB
Hydroquinone SCHEMBL8024416 0.85 ALDH1A1 (0.59) ALDH1A1L3MBTL1PKMNR4A2NR4A1
Hydroquinone SCHEMBL7626940 0.85 ALDH1A1 (0.59) ALDH1A1L3MBTL1PKMNR4A2NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108727769-A A kind of phone housing ABS composite material 安徽酷米智能科技有限公司 2018-11-02 CN disclosed
US-7396486-B2 Polymerizable mixtures WACKER CHEMIE AG (DE) 2008-07-08 US disclosed
US-20060097224-A1 Polymerisable mixtures WACKER CHEMIE AG (DE) 2006-05-11 US disclosed
US-5788880-A Liquid-crystalline organosiloxanes containing chiral dianhydrohexitol derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1998-08-04 US disclosed
EP-0291884-B1 ORGANOPOLYSILOXANES WHICH EXHIBIT LIQUID CRYSTALLINITY AT LOW TEMPERATURES, AND A METHOD FOR THEIR PREPARATION TORAY SILICONE COMPANY, LIMITED (JP) 1992-01-02 EP disclosed
US-4981607-A Liquid-crystalline organopolysiloxanes and methods for their preparation TORAY SILICONE COMPANY LIMITED (JP) 1991-01-01 US disclosed
EP-0338576-A2 Liquid-crystalline organopolysiloxanes and methods for their preparation TORAY SILICONE COMPANY, LIMITED (JP) 1989-10-25 EP disclosed
EP-0291884-A2 Organopolysiloxanes which exhibit liquid crystallinity at low temperatures, and a method for their preparation TORAY SILICONE COMPANY, LIMITED (JP) 1988-11-23 EP disclosed