SCHEMBL5090338

SCHEMBL5090338

C=CCOc1ccc(C(=O)O)cc1.N#Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.50
ALDH1A1 P00352 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PKM P14618 1/20 0.47
ABCB1 P08183 1/20 0.46
HPGD P15428 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
BACE1 P56817 1/20 0.46
FFAR1 O14842 1/20 0.46
CHRNB2 P17787 1/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA4 P43681 1/20 0.45
MAP4K4 O95819 1/20 0.45
MAPT P10636 1/20 0.45
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
MMP3 P08254 3/20 0.44
MMP1 P03956 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5095997 0.89 ALDH1A1 (0.58) ALDH1A1L3MBTL1PKMBACE1FFAR1
Benzoic Acid SCHEMBL9750866 0.88 FFAR1 (0.55) ALDH1A1L3MBTL1PKMBACE1FFAR1
4-Cyanophenol SCHEMBL28947740 0.87 ALDH1A1 (0.50) MMP2ALDH1A1L3MBTL1PKMFFAR1
SCHEMBL5840304 0.86 ALDH1A1 (0.61) ALDH1A1L3MBTL1PKMFFAR1CHRNB2
Hydrochloric Acid SCHEMBL8986262 0.85 ALDH1A1 (0.59) ALDH1A1L3MBTL1PKMFFAR1CHRNB2
Benzene SCHEMBL28158854 0.83 ALDH1A1 (0.65) ALDH1A1L3MBTL1PKMFFAR1CHRNB2
SCHEMBL2356935 0.83 MMP2 (0.50) MMP2ALDH1A1HPGDMAPTMMP3
SCHEMBL5855876 0.83 MMP2 (0.48) MMP2ALDH1A1MAPTMMP3MMP1
SCHEMBL10581417 0.83 MMP2 (0.48) MMP2ALDH1A1MAPTMMP3MMP1
SCHEMBL1494070 0.82 THRB (0.60) MMP2ALDH1A1L3MBTL1PKMABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396486-B2 Polymerizable mixtures WACKER CHEMIE AG (DE) 2008-07-08 US disclosed
US-20060097224-A1 Polymerisable mixtures WACKER CHEMIE AG (DE) 2006-05-11 US disclosed