Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.41 |
| ▸ | ALPL | P05186 | 4/20 | 0.41 |
| ▸ | XIAP | P98170 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096089 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2ABCG2GAAENPP3 | |
| SCHEMBL5101870 | 0.81 | APP (0.52) | ALDH1A1ABCG2 | |
| SCHEMBL1383268 | 0.80 | ABCG2 (0.43) | ALDH1A1ABCG2ABCB1TNFRSF1AMEN1 | |
| SCHEMBL1385627 | 0.80 | ABCG2 (0.43) | ALDH1A1SMN1; SMN2ABCG2CA1CA2 | |
| SCHEMBL5096117 | 0.80 | APP (0.53) | ALDH1A1ABCG2MAPTKDM4EKMT2A | |
| SCHEMBL1384115 | 0.79 | ENPP3 (0.56) | ALDH1A1SMN1; SMN2ENPP3ALPLXIAP | |
| SCHEMBL5101978 | 0.71 | ENPP3 (0.50) | ALDH1A1SMN1; SMN2GAAENPP3ALPL | |
| SCHEMBL18131009 | 0.70 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2GAAENPP3ALPL | |
| SCHEMBL5093439 | 0.70 | TSHR (0.46) | ALDH1A1GAAENPP3ALPLXIAP | |
| SCHEMBL28231525 | 0.68 | ALOX15 (0.54) | ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | claimed |
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | HSPB1, HSF1, HSPE1 | ALDH1A1 1129/4885SMN1; SMN2 315/4885ABCG2 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.