SCHEMBL509647

SCHEMBL509647

CCCCCOC(=O)OC(=O)OCCCCC

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.64
EPHX1 P07099 1/20 0.54
SOAT1 P35610 1/20 0.52
ALDH1A1 P00352 2/20 0.52
TSHR P16473 4/20 0.52
HCAR2 Q8TDS4 2/20 0.50
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48
RAD52 P43351 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ATM Q13315 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
FAAH O00519 1/20 0.47
LMNA P02545 1/20 0.47
ACHE P22303 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723100 0.98 NAAA (0.68) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL8724266 0.98 NAAA (0.68) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL27282395 0.98 NAAA (0.68) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL14245528 0.98 NAAA (0.68) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL8726315 0.98 NAAA (0.68) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL8722217 0.98 NAAA (0.68) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL8726313 0.98 NAAA (0.68) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL40274 0.92 ALDH1A1 (0.61) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL5493391 0.91 SOAT1 (0.62) NAAAEPHX1SOAT1ALDH1A1TSHR
SCHEMBL5491656 0.91 SOAT1 (0.62) NAAAEPHX1SOAT1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5220029-A N-acyl derivatives of thiazolinone hydazones VITEK SYSTEMS, INC. (US) 1993-06-15 US claimed
US-5039738-A Reacting aminoorganosiloxane with dialkyl pyrocarbonate or oxalate UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION (US) 1991-08-13 US claimed
WO-2023153303-A1 PHOTOCURABLE COMPOSITION, OPTICAL LAMINATE, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2023-08-17 WO disclosed
CN-112424269-B Resin composition for foam, and method for producing foam 株式会社钟化 2023-02-28 CN disclosed
EP-3816216-A1 RESIN COMPOSITION FOR FOAM, FOAM, AND PRODUCTION METHOD OF FOAM KANEKA CORPORATION (JP) 2021-05-05 EP disclosed
CN-112424269-A Resin composition for foam, and method for producing foam 株式会社钟化 2021-02-26 CN disclosed
WO-2020196864-A1 FOAM, SOUND-ABSORBING MATERIAL, RESIN COMPOSITION, SOUND-ABSORBING METHOD, SOUND-ABSORBING STRUCTURE, SOUND-ABSORBING STRUCTURE PRODUCTION METHOD, SOUND-ABSORBING MATERIAL PRODUCTION METHOD, BUILDING, AND VEHICLE 株式会社カネカ 2020-10-01 WO disclosed
EP-2938190-B1 MACROCYCLIC PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2017-11-08 EP disclosed
US-20170273306-A1 MACROCYCLIC PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2017-09-28 US disclosed
US-9681664-B2 Macrocyclic picolinamides as fungicides DOW AGROSCIENCES LLC (US) 2017-06-20 US disclosed
EP-2537839-B1 B-DIHYDROFURAN DERIVING COMPOUND, METHOD FOR PRODUCING B-DIHYDROFURAN DERIVING COMPOUND OR B-TETRAHYDROFURAN DERIVING COMPOUND, B -GLYCOSIDE COMPOUND, METHOD FOR PRODUCING B-GLYCOSIDE COMPOUND, AND METHOD FOR PRODUCING 4'-ETHYNYL D4T AND ANALOGUE COMPOUNDS THEREOF NISSAN CHEMICAL IND LTD (JP) 2016-12-14 EP disclosed
EP-0557408-A1 IMIDAZOLIDINONE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1993-09-01 EP disclosed
US-5231211-A Polyetheramine catalysts for reaction of organohaloformates PPG INDUSTRIES, INC. (US) 1993-07-27 US disclosed
EP-0321296-B1 LIPID DERIVATIVES THEIR PREPARATION AND USE SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1992-11-11 EP disclosed
US-5138067-A PAF antagonists, antithrombotic, antivasoconstricting, antibronchoconstricting or antitumor agents SHIONOGI & CO. LTD. (JP) 1992-08-11 US disclosed
EP-0490402-A2 Emulsions containing modified aminoorganosiloxane impart reduced yellowing when used as fabric softeners OSi Specialties, Inc. (US) 1992-06-17 EP disclosed
WO-1992007567-A1 IMIDAZOLIDINONE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1992-05-14 WO disclosed
US-5047540-A Platelet Activating Factor Antagonists and Antitumor Agents SHIONOGI & CO., LTD. (JP) 1991-09-10 US disclosed
US-5039738-A Reacting aminoorganosiloxane with dialkyl pyrocarbonate or oxalate UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION (US) 1991-08-13 US disclosed
EP-0321296-A1 Lipid derivatives their preparation and use SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1989-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170273306-A1 MACROCYCLIC PICOLINAMIDES AS FUNGICIDES FKBP14, FKBP2, CYP4F12 NAAA 2589/4885EPHX1 1223/4885SOAT1 2527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.