SCHEMBL50966

SCHEMBL50966

Cc1nc(C)c(S(=O)(=O)Cl)s1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 1/20 0.32
KIT P10721 1/20 0.32
GAA P10253 1/20 0.32
CHRM5 P08912 1/20 0.32
TP53 P04637 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1177587 0.80 ALDH1A1 (0.44)
SCHEMBL1640359 0.79 ALDH1A1 (0.34) NPY5RKITGAACHRM5TP53
SCHEMBL50995 0.79 CA12 (0.40) KITGAACHRM5TP53THRB
SCHEMBL761873 0.78 NOS1 (0.46) GAA
SCHEMBL4902068 0.77 TP53 (0.34) KITGAACHRM5TP53THRB
Fluoride SCHEMBL27351745 0.76 GAA (0.34) NPY5RKITGAACHRM5TP53
Hydrochloric Acid SCHEMBL27291930 0.76 GAA (0.34) NPY5RKITGAACHRM5TP53
SCHEMBL21993160 0.76 GAA (0.34) KITGAACHRM5TP53THRB
SCHEMBL23497255 0.75 KMT2A (0.44) GAA
SCHEMBL14969351 0.74 CA12 (0.39) NPY5RKITGAATP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116874-A1 HETEROAROMATIC INDOLESULFONAMIDES SEED THERAPEUTICS INC (US) 2026-04-30 US disclosed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 US disclosed
EP-4704836-A1 HETEROAROMATIC INDOLESULFONAMIDES Seed Therapeutics, Inc (US) 2026-03-11 EP disclosed
EP-4662208-A1 COMPOUNDS AND COMPOSITIONS FOR SELECTIVE DEGRADATION OF ENGINEERED PROTEINS Celgene Corporation (US) 2025-12-17 EP disclosed
EP-3728194-B1 QUINOLINE SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS OTAGO INNOVATION LTD (NZ) 2025-06-04 EP disclosed
WO-2025104079-A1 SALICYLIC ACID AND PICOLINIC ACID DERIVATIVES AS INHIBITORS OF ENERGY COUPLING FACTOR (ECF) TRANSPORTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2025-05-22 WO disclosed
US-20250145589-A1 PYRIDINE DERIVATIVE AND USE THEREOF SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) 2025-05-08 US disclosed
US-20250115687-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORP USA (US) 2025-04-10 US disclosed
WO-2025075722-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-04-10 WO disclosed
US-20250101003-A1 SPIROCYCLIC CAV2.3 ANTAGONISTS LARIO THERAPEUTICS LIMITED (GB) 2025-03-27 US disclosed
EP-0719266-A1 HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS PFIZER INC. (US) 1996-07-03 EP disclosed
US-5506242-A METALLOELASTASE INHIBITOR; TREATS EMPHYSEMA CIBA-GEIGY CORPORATION (US) 1996-04-09 US disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
US-5455258-A Useful as inhibitors of matrix-degrading metalloproteinase enzymes such as stromelysin and/or collegenase CIBA-GEIGY CORPORATION (US) 1995-10-03 US disclosed
EP-0659181-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1995-06-28 EP disclosed
WO-1995007908-A1 HETEROARYLAMINO AND HETEROARYLSULFONAMIDO SUBSTITUTED 3-BENZYLAMINOMETHYL PIPERIDINES AND RELATED COMPOUNDS PFIZER INC. (US) 1995-03-23 WO disclosed
EP-0606046-A1 Arylsulfonamido-substituted hydroxamic acids CIBA-GEIGY AG (CH) 1994-07-13 EP disclosed
WO-1994005639-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1994-03-17 WO disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof CYP4A11, CYP4B1, CYP4A22 NPY5R 2222/4885KIT 4736/4885GAA 940/4885
US-20260116874-A1 HETEROAROMATIC INDOLESULFONAMIDES DCAF1, DCAF15, DDX39B NPY5R 3731/4885KIT 2898/4885GAA 4707/4885
US-20250145589-A1 PYRIDINE DERIVATIVE AND USE THEREOF KRAS, NRAS, BRAF NPY5R 4443/4885KIT 1162/4885GAA 1860/4885
US-20250101003-A1 SPIROCYCLIC CAV2.3 ANTAGONISTS CACNA1A, CACNA1E, CACNA1S NPY5R 655/4885KIT 4709/4885GAA 1819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.