Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.40 |
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835387 | 0.89 | HAO1 (0.39) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL2833710 | 0.77 | FFAR1 (0.35) | FFAR1FFAR4MMP2MMP12PTPN7 | |
| SCHEMBL2830660 | 0.75 | MMP2 (0.43) | FFAR1FFAR4MMP2MMP12MAPT | |
| SCHEMBL5666494 | 0.74 | MMP2 (0.48) | FFAR1FFAR4MMP2MMP12MAPT | |
| SCHEMBL22748649 | 0.74 | FFAR1 (0.49) | FFAR1FFAR4MMP2MMP12PTPN7 | |
| SCHEMBL2831444 | 0.74 | FFAR1 (0.46) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL6937361 | 0.73 | MMP2 (0.69) | FFAR1FFAR4MMP2MMP12MEN1 | |
| SCHEMBL20556393 | 0.72 | FFAR1 (0.48) | FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL5804625 | 0.72 | GPR84 (0.48) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL9243477 | 0.72 | RARB (0.54) | GPR84ALDH1A1PLK1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442475-B2 | Cyanopyridone derivatives as liquid crystals | MERCK PATENT GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-7442475-B2 | Cyanopyridone derivatives as liquid crystals | MERCK PATENT GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20060165916-A1 | Cyanopyridone derivatives as liquid crystals | MERCK PATENT GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1594842-A1 | CYANOPYRIDONE DERIVATIVES AS LIQUID CRYSTALS | MERCK PATENT GmbH (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074253-A1 | CYANOPYRIDONE DERIVATIVES AS LIQUID CRYSTALS | MERCK PATENT GMBH (DE) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165916-A1 | Cyanopyridone derivatives as liquid crystals | EPM2A, ACMSD, CSPP1 | FFAR1 2742/4885FFAR4 3123/4885MMP2 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.