Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509690 | 0.83 | KDM4E (0.38) | MAPTKDM4EPOLBTSHRHPGD | |
| Water SCHEMBL28215001 | 0.83 | KDM4E (0.56) | MAPTKDM4EPOLBTSHRHPGD | |
| SCHEMBL509946 | 0.83 | KDM4E (0.46) | MAPTKDM4EPOLBTSHRHPGD | |
| SCHEMBL6829396 | 0.82 | MAPT (0.50) | MAPTKDM4EPOLBTSHRHPGD | |
| SCHEMBL509440 | 0.81 | KDM4E (0.58) | MAPTKDM4EPOLBTSHRHPGD | |
| Hydrochloric Acid SCHEMBL2529687 | 0.79 | KDM4E (0.56) | MAPTKDM4EPOLBTSHRHPGD | |
| SCHEMBL6589469 | 0.77 | RXRA (0.40) | MAPTKDM4EPOLBFFAR1KMT2A | |
| SCHEMBL6471566 | 0.76 | TSHR (0.47) | MAPTKDM4ETSHRFFAR1CASP1 | |
| SCHEMBL29174272 | 0.74 | ALDH1A1 (0.37) | MAPTKDM4EPOLBTSHRHPGD | |
| SCHEMBL508942 | 0.73 | KDM4E (0.50) | MAPTKDM4EPOLBTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8470738-B2 | Pyridazinone compound and herbicide containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2188264-B1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-20100216642-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-0809629-B1 | 2-PHENYL-SUBSTITUTED HETEROCYCLIC 1,3-KETONOLS AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6746990-B2 | INSECTICIDES, ACARICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | FISCHER REINER (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6358887-B1 | PREEMERGENCE, POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-19 | — | — | US | disclosed |
| EP-0809629-A1 | 2-PHENYL-SUBSTITUTED HETEROCYCLIC 1,3-KETONOLS AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025395-A1 | 2-PHENYL-SUBSTITUTED HETEROCYCLIC 1,3-KETONOLS AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | C5, C1S, WEE1 | MAPT 4297/4885KDM4E 3295/4885POLB 3763/4885 |
| US-20100216642-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | WEE1, WEE2, CBR3 | MAPT 4247/4885KDM4E 1987/4885POLB 3977/4885 |
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | CYP19A1, DDT, CYP8B1 | MAPT 4613/4885KDM4E 215/4885POLB 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.