Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099695 | 1.00 | GAA (0.41) | GAAKMT2AMEN1CA1CA2 | |
| SCHEMBL9594005 | 1.00 | GAA (0.41) | GAAKMT2AMEN1CA1CA2 | |
| SCHEMBL9522957 | 0.86 | GAA (0.43) | GAAKMT2AMEN1CA1CA2 | |
| SCHEMBL9592203 | 0.84 | LMNA (0.41) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL9593680 | 0.84 | LMNA (0.41) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL10964785 | 0.84 | LMNA (0.41) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL1869422 | 0.84 | MMP9 (0.45) | GAAKMT2AMEN1CA1CA2 | |
| SCHEMBL10806036 | 0.84 | GAA (0.42) | GAAKMT2AMEN1CA1CA2 | |
| SCHEMBL4372757 | 0.84 | MMP9 (0.45) | GAAKMT2AMEN1CA1CA2 | |
| SCHEMBL2325722 | 0.84 | MMP9 (0.45) | GAAKMT2AMEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368580-B2 | Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | LES LABORATORIES SERVIER (FR) | 2008-05-06 | — | — | US | disclosed |
| US-7358372-B2 | Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | LES LABORATORIES SERVIER (FR) | 2008-04-15 | — | — | US | disclosed |
| US-20060189813-A1 | Novel method for the synthesis of perinidopril and the pharmaceutically acceptable salts thereof | LES LABORATOIRES SERVIER (FR) | 2006-08-24 | — | — | US | disclosed |
| US-20060183920-A1 | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | LES LABORATOIRES SERVIER (FR) | 2006-08-17 | — | — | US | disclosed |
| EP-0595345-B1 | Process for producing alanylglutamine | KYOWA HAKKO KOGYO KK (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5550283-A | Process for producing alanylglutamine | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| US-5380934-A | Process for producing alanylgutamine | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0595345-A1 | Process for producing alanylglutamine | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-4699949-A | Hardening of acid-hardenable compositions containing a blocked hardening catalyst, using heat | CIBA-GEIGY CORPORATION (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0132225-B1 | CURING OF ACID-CURABLE COMPOSITIONS CONTAINING A BLOCKED CATALYST WITH THE AID OF HEAT | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| US-4596594-A | For removal of unwanted vegetation | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | disclosed |
| US-4447259-A | 2-(Substituted phenoxy)propionic acid derivatives and their uses for herbicidal purposes | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183920-A1 | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | ACE, QDPR, REN | GAA 947/4885KMT2A 3052/4885MEN1 4611/4885 |
| US-20060189813-A1 | Novel method for the synthesis of perinidopril and the pharmaceutically acceptable salts thereof | QDPR, ACE, REN | GAA 766/4885KMT2A 2847/4885MEN1 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.