Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096786 | 0.86 | COMT (0.58) | ALPLALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL5140233 | 0.86 | ROCK2 (0.47) | ALPLALDH1A1NPC1RAB9ACYP2D6 | |
| SCHEMBL14311768 | 0.82 | CYP11B1 (0.57) | ALPLNPC1RAB9AMAPTCYP11B1 | |
| SCHEMBL5096941 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1NPC1RAB9ACYP2D6CYP1A2 | |
| SCHEMBL1602901 | 0.79 | MAPT (0.54) | ALPLCYP19A1MAPTCYP11B1CYP11B2 | |
| SCHEMBL5096712 | 0.79 | CYP11B1 (0.59) | RAB9ACYP2D6CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL5100746 | 0.78 | CYP11B1 (0.47) | ALDH1A1NPC1RAB9ACYP2D6CYP2C9 | |
| SCHEMBL5104024 | 0.78 | HRH3 (0.48) | CYP19A1CYP11B1CYP11B2HPGDCOMT | |
| SCHEMBL5111022 | 0.78 | FGFR1 (0.49) | ALPLALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL5109720 | 0.77 | CYP11B1 (0.43) | MAPTCYP11B1CYP11B2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004100-A2 | THERAPEUTIC COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-01-10 | — | — | WO | disclosed |