SCHEMBL510069

SCHEMBL510069

CCCCNc1ccc(C(=O)OC(C)N(CC)CC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
RAB9A P51151 3/20 0.58
KDM4E B2RXH2 1/20 0.58
GMNN O75496 1/20 0.58
BLM P54132 1/20 0.58
PMP22 Q01453 1/20 0.58
SCN5A Q14524 2/20 0.56
CYP1A2 P05177 1/20 0.56
MAOA P21397 1/20 0.56
CNR1 P21554 1/20 0.56
DRD4 P21917 1/20 0.56
ACHE P22303 1/20 0.56
HRH2 P25021 1/20 0.56
HTR2A P28223 1/20 0.56
HTR2C P28335 1/20 0.56
MAPK1 P28482 1/20 0.56
NTSR1 P30989 1/20 0.56
HRH1 P35367 1/20 0.56
DRD3 P35462 1/20 0.56
SCN1A P35498 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL510380 1.00 LMNA (0.58) LMNARAB9AKDM4EGMNNBLM
SCHEMBL29020376 0.85 LMNA (0.59) LMNARAB9AKDM4EGMNNBLM
Butane SCHEMBL6810096 0.83 RAB9A (0.56) LMNARAB9AKDM4EGMNNBLM
SCHEMBL5925590 0.82 ALDH1A1 (0.44) LMNARAB9AKDM4EMAPK1TSHR
Butane SCHEMBL21438842 0.81 LMNA (0.55) LMNARAB9AKDM4EGMNNBLM
SCHEMBL1118828 0.81 ALDH1A1 (0.43) LMNARAB9AKDM4EBLMMAPK1
SCHEMBL5925519 0.80 HSD17B10 (0.55) LMNARAB9AKDM4EBLMCYP1A2
SCHEMBL14149520 0.78 SCN5A (0.68) LMNARAB9AKDM4EGMNNBLM
Hydrochloric Acid SCHEMBL11345886 0.77 LMNA (0.50) LMNARAB9AKDM4EGMNNBLM
SCHEMBL11341345 0.76 LMNA (0.50) LMNARAB9AKDM4EGMNNBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2457566-A1 EXTERNAL PREPARATION CONTAINING NSAIDs AND METHOD FOR PRODUCING THE EXTERNAL PREPARATION Next 21 K.K. (JP) 2012-05-30 EP claimed
CN-119894520-A External skin preparation composition 志瑞亚新药工业株式会社 2025-04-25 CN disclosed
WO-2024058193-A1 COMPOSITION FOR EXTERNAL PREPARATION FOR SKIN ゼリア新薬工業株式会社 2024-03-21 WO disclosed
US-11833123-B2 Pharmaceutical composition KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) 2023-12-05 US disclosed
CN-113993593-A External preparation composition 志瑞亚新药工业株式会社 2022-01-28 CN disclosed
US-20210346323-A1 PHARMACEUTICAL COMPOSITION KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) 2021-11-11 US disclosed
WO-2020251017-A1 COMPOSITION FOR EXTERNAL APPLICATION ゼリア新薬工業株式会社 2020-12-17 WO disclosed
US-9505732-B2 Auto magnetic metal salen complex compound IHI CORPORATION (JP) 2016-11-29 US disclosed
US-20140336144-A1 External Preparation Containing NSAIDS And Method For Producing The External Preparation NEXT21 K.K. (JP) 2014-11-13 US disclosed
US-8354393-B2 Film preparation and process for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-01-15 US disclosed
US-20090142389-A1 HYDROGEL SHEET AND PRODUCTION METHOD THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-06-04 US disclosed
EP-2021031-A1 HYDROGEL SHEET AND PRODUCTION METHOD THEREOF Shin-Etsu Chemical Co., Ltd. (JP) 2009-02-11 EP disclosed
WO-2007142280-A1 HYDROGEL SHEET AND PRODUCTION METHOD THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-12-13 WO disclosed
US-20060159632-A1 Drug formulation for mouth or pharynx comprising local anesthetic MEDRX CO., LTD. (JP) 2006-07-20 US disclosed
US-20050244483-A1 Film preparation and process for preparing the same SHIN-ETSU CHEMICAL CO., LTD. 2005-11-03 US disclosed
EP-1591106-A1 Film preparation and process for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-11-02 EP disclosed
EP-0781546-B1 A multi-layered film preparation SANWA KAGAKU KENKYUSHO CO (JP) 2001-03-07 EP disclosed
US-5914118-A DRUG-CONTAINING LAYER CONTAINING WATER-SOLUBLE HIGH MOLECULAR WEIGHT COMPOUND AS BASE MATERIAL, DIFFICULT TO DISSOLVE NON-ADHESIVE LAYER ON SURFACE OF DRUG LAYER, ADHESIVE COMPOUND ON OTHER SURFACE OF DRUG LAYER SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1999-06-22 US disclosed
EP-0781546-A1 A multi-layered film preparation SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1997-07-02 EP disclosed
US-4983385-A For wet body surface, water-soluble polymer hydrogel, methacrylate copolymer, solubilizer SUNSTAR KABUSHIKI KAISHA (JP) 1991-01-08 US disclosed