Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.35 |
| ▸ | PDE1A | P54750 | 3/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131938 | 0.86 | DHODH (0.40) | DHODHPDE3BPDE3APDE1APDE1B | |
| SCHEMBL6131929 | 0.82 | KMT2A (0.39) | DHODHPDE3BPDE3APDE1APDE1B | |
| SCHEMBL29565451 | 0.77 | KDM4E (0.45) | DHODHKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23800906 | 0.77 | KDM4E (0.45) | DHODHKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6131930 | 0.77 | L3MBTL1 (0.39) | PDE3BPDE3APDE1APDE1BPDE1C | |
| SCHEMBL7785460 | 0.76 | MAPT (0.39) | DHODHPDE3BPDE3APDE1APDE1B | |
| SCHEMBL4798246 | 0.73 | PLA2G2A (0.41) | KDM4EALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL26290022 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL1331927 | 0.72 | KDM4E (0.33) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL5107478 | 0.71 | NR4A2 (0.37) | KDM4EALDH1A1HPGDMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040191520-A1 | Photochromic articles with reduced temperature dependency and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-30 | — | — | US | claimed |
| US-7320826-B2 | comprises 3-(4-methoxyphenyl)-3-phenyl-6,7,10,11-tetramethoxy-13-ethyl-13-hydroxy-13H-3H-indeno[2,'3,'3,4]naphtho[1,2-b]pyran; for activation via actinic radiation; improved optical density response; ophthalmic lens | PPG INDUSTRIES OHIO, INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-20040191520-A1 | Photochromic articles with reduced temperature dependency and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-30 | — | — | US | disclosed |