Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19317172 | 0.90 | ESR1 (0.69) | ESR1ESR2POLBSTAT3NPSR1 | |
| SCHEMBL9566633 | 0.82 | ESR1 (0.73) | ESR1ESR2POLBSTAT3NPSR1 | |
| SCHEMBL8615277 | 0.81 | ESR1 (1.00) | ESR1ESR2POLBNPC1NR1H3 | |
| SCHEMBL18589041 | 0.81 | ESR1 (0.68) | ESR1ESR2NPC1NR1H3CA12 | |
| SCHEMBL9571698 | 0.81 | ESR1 (0.71) | ESR1ESR2POLBSTAT3NPSR1 | |
| SCHEMBL3619832 | 0.80 | KMT2A (0.64) | ESR1ESR2NR1H3CA12CA1 | |
| SCHEMBL30390220 | 0.80 | KMT2A (0.64) | ESR1ESR2NR1H3CA12CA1 | |
| N-Phenyl-Phthalimide SCHEMBL123618 | 0.80 | KMT2A (0.68) | ESR1NPSR1NR1H3CA12CA1 | |
| SCHEMBL19773976 | 0.80 | KMT2A (0.68) | ESR1NPSR1NR1H3CA12CA1 | |
| N-Phenyl-Phthalimide SCHEMBL29819622 | 0.80 | KMT2A (0.68) | ESR1NPSR1NR1H3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103497337-B | A kind of preparation method of Polythioetherimide | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-18 | — | — | CN | claimed |
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| EP-4157823-A1 | COMPOUNDS | JANSSEN Pharmaceutica NV (BE) | 2023-04-05 | — | — | EP | disclosed |
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |
| US-10294255-B1 | Multifunctional crosslinking agent, crosslinked polymer, and method of making same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2019-05-21 | — | — | US | disclosed |
| EP-2915804-B1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF AS TNF ALPHA INHIBITORS | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-03-27 | — | — | EP | disclosed |
| US-20170256718-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-09-07 | — | — | US | disclosed |
| US-20170256718-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-09-07 | — | — | US | disclosed |
| US-9624215-B2 | Amine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2017-04-18 | — | — | US | disclosed |
| CN-103497337-B | A kind of preparation method of Polythioetherimide | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-18 | — | — | CN | disclosed |
| US-20150299189-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2915804-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2015-09-09 | — | — | EP | disclosed |
| CN-103319715-B | Hydrolysis-resistanteasy-processable easy-processable polythioetherimide resin material and preparation method thereof | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-104311825-A | Phenolphthalein type copolyimide and preparation method thereof | NINGBO INST MATERIALS TECHNOLOGY & ENG CAS | 2015-01-28 | — | — | CN | disclosed |
| US-7425650-B1 | Synthesis of asymmetric tetracarboxylic acids and corresponding dianhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2008-09-16 | — | — | US | disclosed |
| US-6395907-B1 | Preparation of polyaromatic-ethynyl thermal setting agents | VIRGINIA COMMONWEALTH UNIVERSITY | 2002-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | NLRP3, NLRP1, IL1B | ESR1 453/4885ESR2 573/4885POLB 3231/4885 |
| US-20170256718-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE | OR10J3, YAP1, OR51E2 | ESR1 113/4885ESR2 317/4885POLB 3816/4885 |
| US-20150299189-A1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF | HRH4, CLIC4, KRT18 | ESR1 3383/4885ESR2 3072/4885POLB 2236/4885 |
| US-10294255-B1 | Multifunctional crosslinking agent, crosslinked polymer, and method of making same | PARN, PAICS, PAM | ESR1 4181/4885ESR2 3767/4885POLB 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.