Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812570 | 0.91 | PSMB1 (0.61) | ALDH1A1KDM4EHRH3PSMB1PSMB5 | |
| SCHEMBL1807911 | 0.91 | PSMB1 (0.61) | ALDH1A1KDM4EHRH3PSMB1PSMB5 | |
| SCHEMBL5101810 | 0.82 | TACR2 (0.49) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL991354 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4ESMN1; SMN2GAAHRH3 | |
| Hydrochloric Acid SCHEMBL7887532 | 0.76 | ALDH1A1 (0.74) | ALDH1A1KDM4ESMN1; SMN2GAAHRH3 | |
| SCHEMBL1976504 | 0.75 | PLK1 (0.55) | ALDH1A1KDM4ESMN1; SMN2MAPTNPC1 | |
| SCHEMBL11757768 | 0.75 | SMN1; SMN2 (0.62) | ALDH1A1KDM4ESMN1; SMN2GAAHRH3 | |
| SCHEMBL63569 | 0.74 | SMN1; SMN2 (0.72) | ALDH1A1KDM4ESMN1; SMN2GAAHRH3 | |
| SCHEMBL3366608 | 0.74 | LTA4H (0.78) | ALDH1A1KDM4ESMN1; SMN2GAAPSMB1 | |
| SCHEMBL5111664 | 0.74 | MAOB (0.49) | KDM4EGAAPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342027-B2 | 1-phenylpiperidin-3-one derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2008-03-11 | — | — | US | disclosed |
| US-20050234057-A1 | 1-Phenylpiperidin-3-one derivatives and processes for the preparation thereof | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 2005-10-20 | — | — | US | disclosed |
| WO-2004011457-A1 | 1-PHENYLPIPERIDIN-3-ONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234057-A1 | 1-Phenylpiperidin-3-one derivatives and processes for the preparation thereof | CTRL, PRCP, CLPP | ALDH1A1 740/4885KDM4E 2744/4885SMN1; SMN2 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.