Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.49 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5106711 | 1.00 | PTGER4 (0.53) | PTGER4PTGER2PTGER3PTGER1MAP3K7 | |
| SCHEMBL5407245 | 0.86 | GAA (0.64) | PTGER4PTGER2PTGER3PTGER1MAP3K7 | |
| SCHEMBL5407247 | 0.86 | GAA (0.64) | PTGER4PTGER2PTGER3PTGER1MAP3K7 | |
| SCHEMBL5411015 | 0.84 | MEN1 (0.57) | PTGER4PTGER2PTGER3PTGER1MAP3K7 | |
| SCHEMBL5411022 | 0.84 | MEN1 (0.57) | PTGER4PTGER2PTGER3PTGER1MAP3K7 | |
| SCHEMBL5121868 | 0.82 | ADORA3 (0.44) | PKMMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30556899 | 0.81 | ADORA3 (0.44) | PKMMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6593163 | 0.81 | GAA (0.58) | PTGER4PTGER2PTGER3PTGER1GAA | |
| SCHEMBL6593156 | 0.81 | GAA (0.58) | PTGER4PTGER2PTGER3PTGER1GAA | |
| SCHEMBL4703265 | 0.78 | ALKBH1 (0.51) | PTGER1PKMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | PTGER4 1928/4885PTGER2 3643/4885PTGER3 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.