Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5106015 | 0.99 | ADAM17 (0.44) | ADAM17BCL2L1MCL1SPHK2SPHK1 | |
| SCHEMBL1015026 | 0.87 | BCL2L1 (0.44) | ADAM17BCL2L1MCL1SPHK2SPHK1 | |
| SCHEMBL1015028 | 0.87 | BCL2L1 (0.44) | ADAM17BCL2L1MCL1SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL5106017 | 0.86 | BCL2L1 (0.43) | ADAM17BCL2L1MCL1SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL5112794 | 0.86 | BCL2L1 (0.43) | ADAM17BCL2L1MCL1SPHK2SPHK1 | |
| SCHEMBL14277999 | 0.85 | POLB (0.46) | ADAM17BCL2L1MCL1POLBMEN1 | |
| SCHEMBL14301679 | 0.83 | POLB (0.44) | ADAM17BCL2L1MCL1POLBMEN1 | |
| SCHEMBL5570893 | 0.83 | BCL2L1 (0.43) | ADAM17BCL2L1MCL1POLBMEN1 | |
| SCHEMBL14364377 | 0.83 | POLB (0.43) | ADAM17BCL2L1MCL1POLBMEN1 | |
| SCHEMBL14364344 | 0.83 | POLB (0.43) | ADAM17BCL2L1MCL1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045530-A1 | Organic Compounds and Their Uses | BRANDL TRIXI | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045530-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | ADAM17 4444/4885BCL2L1 2218/4885MCL1 1531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.