Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | RAF1 | P04049 | 5/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107256 | 0.94 | TRPM8 (0.54) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL5121399 | 0.93 | TRPM8 (0.54) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL5106648 | 0.88 | KMT2A (0.51) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL5110104 | 0.88 | TRPM8 (0.62) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL14078343 | 0.88 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL14078347 | 0.86 | TRPM8 (0.69) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL5301483 | 0.85 | TRPM8 (0.52) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL14078308 | 0.83 | TRPM8 (0.50) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL14078293 | 0.83 | MRGPRX4 (0.52) | MTNR1AMTNR1BMEN1KMT2ATRPM8 | |
| SCHEMBL14078350 | 0.83 | TRPM8 (0.49) | MTNR1AMTNR1BMEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214654-A1 | Substituted Benzyloxy-Phenylmethylamide Derivatives | BAYER HEALTHCARE AG (DE) | 2008-09-04 | — | — | US | disclosed |
| EP-1802600-A1 | SUBSTITUTED 4-BENZYLOXY-PHENYLMETHYLAMIDE DERIVATIVES AS COLD MENTHOL RECEPTOR-1 (CMR-1) ANTAGONITS FOR THE TREATMENT OF UROLOGICAL DISORDERS | Bayer HealthCare AG (DE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040136-A1 | SUBSTITUTED 4-BENZYLOXY-PHENYLMETHYLAMIDE DERIVATIVES AS COLD MENTHOL RECEPTOR-1 (CMR-1) ANTAGONISTS FOR THE TREATMENT OF UROLOGICAL DISORDER | BAYER HEALTHCARE AG (DE) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214654-A1 | Substituted Benzyloxy-Phenylmethylamide Derivatives | OPRL1, ADRA1A, CNR1 | MTNR1A 132/4885MTNR1B 178/4885MEN1 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.