SCHEMBL5111222

SCHEMBL5111222

O=C1C2CC3CC(C2)C(=O)C1C3

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
EPHX2 P34913 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10743497 0.83 TSHR (0.30) TSHR
Adamantane SCHEMBL9651363 0.78 TSHR (0.40) TSHREPHX2
SCHEMBL4721541 0.78 TSHR (0.40) TSHREPHX2
SCHEMBL71132 0.78 TSHR (0.40) TSHREPHX2
SCHEMBL10285140 0.78 TSHR (0.40) TSHREPHX2
SCHEMBL14791313 0.78 TSHR (0.40) TSHREPHX2
SCHEMBL6315184 0.75 TSHR (0.39) TSHREPHX2
SCHEMBL3137075 0.75 MEN1 (0.33)
SCHEMBL1238943 0.73 HSD11B1 (0.32) EPHX2
Ethylene SCHEMBL1617394 0.73 TSHR (0.37) TSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099218-A1 MECHANOCALORIC METHOD SUMITOMO CHEMICAL CO., LTD (JP) 2026-05-15 WO claimed
US-5576355-A INHIBITING HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRUS MOBIL OIL CORP. (US) 1996-11-19 US claimed
EP-0706384-A1 DIAMONDOID DERIVATIVES FOR PHARMACEUTICAL USE MOBIL OIL CORPORATION (US) 1996-04-17 EP claimed
WO-1994028885-A1 DIAMONDOID DERIVATIVES FOR PHARMACEUTICAL USE MOBIL OIL CORPORATION (US) 1994-12-22 WO claimed
US-5298666-A Synthesis of adamantane-2,4-dione MOBIL OIL CORPORATION (US) 1994-03-29 US claimed
WO-2026099218-A1 MECHANOCALORIC METHOD SUMITOMO CHEMICAL CO., LTD (JP) 2026-05-15 WO disclosed
WO-2026099218-A1 MECHANOCALORIC METHOD SUMITOMO CHEMICAL CO., LTD (JP) 2026-05-15 WO disclosed
US-20200181192-A1 DISULFIDE BIOCONJUGATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-06-11 US disclosed
WO-2018201000-A1 DISULFIDE BIOCONJUGATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-11-01 WO disclosed
US-7371778-B2 Spiro and dispiro 1,2,4-trioxolane antimalarials MEDICINES FOR MALARIA VENTURE MMV (CH) 2008-05-13 US disclosed
US-20050256185-A1 Spiro and dispiro 1,2,4-trioxolane antimalarials MEDICINES FOR MALARIA VENTURE MMV (CH) 2005-11-17 US disclosed
US-5576355-A INHIBITING HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRUS MOBIL OIL CORP. (US) 1996-11-19 US disclosed
US-5410092-A Synthesis of adamantane-2,4-dione MOBIL OIL CORPORATION (US) 1995-04-25 US disclosed
US-5410092-A Synthesis of adamantane-2,4-dione MOBIL OIL CORPORATION (US) 1995-04-25 US disclosed
WO-1994028885-A1 DIAMONDOID DERIVATIVES FOR PHARMACEUTICAL USE MOBIL OIL CORPORATION (US) 1994-12-22 WO disclosed
US-5298666-A Synthesis of adamantane-2,4-dione MOBIL OIL CORPORATION (US) 1994-03-29 US disclosed
US-5298666-A Synthesis of adamantane-2,4-dione MOBIL OIL CORPORATION (US) 1994-03-29 US disclosed
EP-0554244-A1 ADAMANTANE POLYMERIC COMPOSITIONS MOBIL OIL CORPORATION (US) 1993-08-11 EP disclosed
WO-1992007018-A1 ADAMANTANE POLYMERIC COMPOSITIONS MOBIL OIL CORPORATION (US) 1992-04-30 WO disclosed
US-5053434-A Diamondoid polymeric compositions MOBIL OIL CORPORATION (US) 1991-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181192-A1 DISULFIDE BIOCONJUGATION P4HB, PDIA6, PDIA5 TSHR 1370/4885EPHX2 2513/4885
US-20050256185-A1 Spiro and dispiro 1,2,4-trioxolane antimalarials DHODH, THPO, SQLE TSHR 2097/4885EPHX2 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.