Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352265 | 0.98 | FDPS (0.67) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL1748837 | 0.95 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL6963840 | 0.94 | FDPS (0.79) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL2818009 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30360547 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30360543 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL8310250 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5689116 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL10417162 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL8907835 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363880-A4 | SYNTHESIS FOR THE PREPARATION OF COMPOUNDS FOR SCREENING AS POTENTIAL TUBULIN BINDING AGENTS | UNIV AUSTRALIAN (AU) | 2008-10-08 | — | — | EP | disclosed |
| US-20050130221-A1 | Synthesis for the preparation of compounds for screening as potential tubulin binding agents | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2005-06-16 | — | — | US | disclosed |
| EP-0974589-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2004-02-18 | — | — | EP | disclosed |
| EP-1363880-A1 | SYNTHESIS FOR THE PREPARATION OF COMPOUNDS FOR SCREENING AS POTENTIAL TUBULIN BINDING AGENTS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002060872-A1 | SYNTHESIS FOR THE PREPARATION OF COMPOUNDS FOR SCREENING AS POTENTIAL TUBULIN BINDING AGENTS | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2002-08-08 | — | — | WO | disclosed |
| US-6248768-B1 | PROSTAGLANDIN INHIBITOR; ANTIINFLAMMATORY AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0974589-A1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130221-A1 | Synthesis for the preparation of compounds for screening as potential tubulin binding agents | TUBB, TUBB3, TUBB1 | FDPS 111/4885ALDH1A1 2568/4885TSHR 4589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.