Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111350 | 0.95 | FDPS (0.69) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL13352265 | 0.94 | FDPS (0.67) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL686103 | 0.94 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL7361734 | 0.93 | FDPS (0.66) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL16067479 | 0.92 | FDPS (0.74) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL1121628 | 0.92 | FDPS (0.73) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL2821372 | 0.92 | FDPS (0.67) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30834674 | 0.92 | FDPS (0.67) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5974454 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL13590011 | 0.90 | FDPS (0.75) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589136-A | Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups | CUTANIX CORP (US) | 2005-03-02 | — | — | CN | claimed |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. | 2003-07-03 | — | — | US | claimed |
| EP-0709361-B1 | Process for the preparation of isovanilline | RHODIA CHIMIE SA (FR) | 1999-02-03 | — | — | EP | claimed |
| US-5786516-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1998-07-28 | — | — | US | claimed |
| US-5648552-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1997-07-15 | — | — | US | claimed |
| EP-0709361-A1 | Process for the preparation of isovanilline | RHONE-POULENC CHIMIE (FR) | 1996-05-01 | — | — | EP | claimed |
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190111044-A1 | 2-PHENETHENYLTETRAHYDRO ISOQUINOLINES USEFUL AS ANTI-HIV COMPOUNDS | Prosetta Antiviral, Inc. | 2019-04-18 | — | — | US | disclosed |
| US-10195189-B2 | 2-phenethenyltetrahydro isoquinolines useful as anti-HIV compounds | Prosetta Antiviral, Inc. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | ALLERGAN, INC. | 2018-06-21 | — | — | US | disclosed |
| US-9895361-B2 | Compositions containing aromatic aldehydes and their use in treatments | ALLERGAN, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170368051-A1 | 2-PHENETHENYLTETRAHYDRO ISOQUINOLINES USEFUL AS ANTI-HIV COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-28 | — | — | US | disclosed |
| EP-3091011-B1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2017-12-27 | — | — | EP | disclosed |
| EP-0470805-B1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PROD (US) | 1994-09-07 | — | — | EP | disclosed |
| WO-1994002465-A1 | INHIBITORS OF c-AMP PHOSPHODIESTERASE AND TNF | RHONE-POULENC RORER LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |
| EP-0569414-A1 | BENZAMIDES | RHONE-POULENC RORER LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012961-A1 | BENZAMIDES | RHONE POULENC RORER LIMITED (GB) | 1992-08-06 | — | — | WO | disclosed |
| EP-0497564-A1 | Benzamides | RHONE POULENC RORER LIMITED (GB) | 1992-08-05 | — | — | EP | disclosed |
| US-5124455-A | Enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0470805-A1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190111044-A1 | 2-PHENETHENYLTETRAHYDRO ISOQUINOLINES USEFUL AS ANTI-HIV COMPOUNDS | MAVS, EIF2AK2, POLRMT | FDPS 1311/4885ALDH1A1 3748/4885TSHR 4860/4885 |
| US-10702515-B2 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | FDPS 1368/4885ALDH1A1 4/4885TSHR 4387/4885 |
| US-20180169086-A1 | COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS | TYR, ALDH2, AOX1 | FDPS 1368/4885ALDH1A1 4/4885TSHR 4387/4885 |
| US-20030124157-A1 | Compositions containing aromatic aldehydes and their use in treatments | TYR, ALDH2, AOX1 | FDPS 1368/4885ALDH1A1 4/4885TSHR 4387/4885 |
| US-10195189-B2 | 2-phenethenyltetrahydro isoquinolines useful as anti-HIV compounds | MAVS, EIF2AK2, POLRMT | FDPS 1311/4885ALDH1A1 3748/4885TSHR 4860/4885 |
| US-20170368051-A1 | 2-PHENETHENYLTETRAHYDRO ISOQUINOLINES USEFUL AS ANTI-HIV COMPOUNDS | MAVS, EIF2AK2, POLRMT | FDPS 1311/4885ALDH1A1 3748/4885TSHR 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.