Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929444 | 0.90 | ALDH1A1 (0.46) | ALDH1A1THRATHRBLMNAMME | |
| SCHEMBL5110736 | 0.90 | ALDH1A1 (0.46) | ALDH1A1THRATHRBLMNAMME | |
| SCHEMBL5109913 | 0.89 | ALDH1A1 (0.46) | ALDH1A1THRATHRBLMNAMME | |
| SCHEMBL5118031 | 0.89 | THRB (0.47) | ALDH1A1THRATHRBLMNAMME | |
| SCHEMBL5110472 | 0.89 | THRB (0.47) | ALDH1A1THRATHRBLMNATACR1 | |
| SCHEMBL4934596 | 0.89 | THRA (0.47) | ALDH1A1THRATHRBLMNATACR1 | |
| SCHEMBL5104439 | 0.89 | THRA (0.47) | ALDH1A1THRATHRBLMNATACR1 | |
| SCHEMBL5722591 | 0.88 | THRB (0.41) | ALDH1A1THRATHRBSMN1; SMN2MRGPRX4 | |
| SCHEMBL4929469 | 0.87 | ALDH1A1 (0.43) | ALDH1A1THRATHRBLMNAMME | |
| SCHEMBL5111651 | 0.87 | THRA (0.61) | ALDH1A1THRATHRBLMNAMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | ALDH1A1 2530/4885THRA 3/4885THRB 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.