Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113466 | 1.00 | HTR1A (0.43) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL4047654 | 0.80 | MTNR1A (0.51) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL4047650 | 0.80 | MTNR1A (0.51) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL4049338 | 0.80 | MTNR1A (0.51) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL14177908 | 0.74 | MTNR1A (0.42) | HTR6KDM4EATM | |
| SCHEMBL14177909 | 0.68 | MTNR1A (0.39) | HTR2AHTR2CHTR6CCNT1CDK9 | |
| SCHEMBL2271779 | 0.64 | HTR1A (0.63) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL4049451 | 0.64 | HTR6 (0.53) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL3324374 | 0.64 | HTR6 (0.53) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL4058308 | 0.64 | HTR6 (0.53) | HTR1AHTR1DHTR1BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388024-B2 | Indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-06-17 | — | — | US | claimed |