Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 7/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113690 | 1.00 | CHRM2 (0.35) | CHRM2CHRM1CHRM3SLC6A1OPRM1 | |
| SCHEMBL5113681 | 0.88 | CHRM2 (0.36) | CHRM2CHRM1CHRM3SLC6A1OPRM1 | |
| SCHEMBL5918459 | 0.83 | OPRM1 (0.35) | SLC6A1OPRM1OPRD1OPRK1 | |
| SCHEMBL5113973 | 0.78 | CHRM5 (0.48) | CHRM2CHRM1CHRM3OPRM1OPRD1 | |
| SCHEMBL5113972 | 0.78 | CHRM5 (0.48) | CHRM2CHRM1CHRM3OPRM1OPRD1 | |
| SCHEMBL5129667 | 0.76 | ALDH1A1 (0.45) | OPRD1OPRK1TSHRALDH1A1LMNA | |
| SCHEMBL5129664 | 0.76 | ALDH1A1 (0.45) | OPRD1OPRK1TSHRALDH1A1LMNA | |
| SCHEMBL6180467 | 0.69 | CHRM2 (0.37) | CHRM2CHRM1CHRM3SLC6A1CYP1A2 | |
| SCHEMBL5113968 | 0.66 | CHRM5 (0.49) | CHRM2CHRM1CHRM3OPRM1OPRK1 | |
| SCHEMBL5129662 | 0.64 | ALDH1A1 (0.46) | OPRD1OPRK1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465751-B2 | 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2008-12-16 | — | — | US | disclosed |