Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 5/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116052 | 0.81 | DRD2 (0.51) | LTA4HDRD2DRD4 | |
| SCHEMBL4889901 | 0.76 | PTGDR2 (0.38) | CHRM2CHRM1CHRM3DRD2DRD4 | |
| SCHEMBL5115681 | 0.74 | TACR3 (0.52) | DRD2DRD4RBP4TSHR | |
| SCHEMBL5145288 | 0.71 | SLC6A2 (0.40) | CHRM1SLC6A1DRD3CYP1A2CYP2D6 | |
| SCHEMBL3681668 | 0.70 | PTGDR2 (0.46) | CHRM1DRD3CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4887368 | 0.70 | CHRM2 (0.33) | CHRM2CHRM1CHRM3SLC6A1DRD3 | |
| SCHEMBL5113690 | 0.69 | CHRM2 (0.35) | CHRM2CHRM1CHRM3SLC6A1CYP1A2 | |
| SCHEMBL5113687 | 0.69 | CHRM2 (0.35) | CHRM2CHRM1CHRM3SLC6A1CYP1A2 | |
| SCHEMBL10938940 | 0.66 | SIGMAR1 (0.60) | LTA4HSLC6A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10939408 | 0.65 | LTA4H (0.52) | LTA4HSLC6A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583741-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories, Limited (IN) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004056767-A1 | 1-SUBSTITUTED-3-PYRROLIDINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2004-07-08 | — | — | WO | disclosed |