SCHEMBL5114953

SCHEMBL5114953

Fc1ccc(/N=N/c2ccc(F)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
SLC22A3 O75751 1/20 0.50
PLAU P00749 1/20 0.50
KMT2A Q03164 10/20 0.48
MEN1 O00255 9/20 0.48
MAPT P10636 8/20 0.48
RAB9A P51151 7/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
GFER P55789 1/20 0.48
NOS3 P29474 2/20 0.48
NOS1 P29475 2/20 0.48
NPC1 O15118 5/20 0.47
TDP1 Q9NUW8 4/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALOX12 P18054 1/20 0.45
THRB P10828 1/20 0.45
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 2/20 0.44
USP2 O75604 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5114955 1.00 SLC22A2 (0.50) SLC22A2SLC22A1SLC22A3PLAUKMT2A
SCHEMBL3282785 0.88 ALDH1A1 (0.67) SLC22A2SLC22A1SLC22A3PLAUKMT2A
SCHEMBL10623038 0.86 MEN1 (0.61) SLC22A2SLC22A1SLC22A3PLAUKMT2A
SCHEMBL10623031 0.86 MEN1 (0.61) SLC22A2SLC22A1SLC22A3PLAUKMT2A
SCHEMBL10816322 0.86 RAB9A (0.43) SLC22A2SLC22A1SLC22A3PLAUKMT2A
SCHEMBL10814297 0.86 ACHE (0.68) SLC22A2SLC22A1SLC22A3PLAUKMT2A
SCHEMBL5982603 0.80 NPC1 (0.67) KMT2AMEN1MAPTRAB9AL3MBTL1
SCHEMBL12069735 0.80 NPC1 (0.67) KMT2AMEN1MAPTRAB9AL3MBTL1
SCHEMBL31186243 0.80 KDM4E (0.52) KMT2AMEN1MAPTRAB9AL3MBTL1
SCHEMBL21242324 0.80 MAPT (0.44) SLC22A2SLC22A1SLC22A3PLAUKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480485-A 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2021-10-08 CN claimed
US-7318964-B2 Fluorene compounds containing various functional groups, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-01-15 US claimed
CN-113480485-B 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2023-04-07 CN disclosed
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN disclosed
CN-110041223-B Method for synthesizing azo compound by taking hydrazine compound as raw material through oxidation 西北师范大学 2021-10-22 CN disclosed
CN-109704987-B Method for synthesizing 2-fluorobenzene amine compound 浙江工业大学 2021-10-15 CN disclosed
CN-113480485-A 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof 甘肃农业大学 2021-10-08 CN disclosed
CN-111978201-A Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2020-11-24 CN disclosed
US-7318964-B2 Fluorene compounds containing various functional groups, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-01-15 US disclosed
US-20030091859-A1 Fluorene compounds containing various functional groups, polymers thereof and el element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-05-15 US disclosed
EP-0067850-B1 BLENDS OF COPOLY (ESTER-CARBONATE) WITH POLYSULFONE GENERAL ELECTRIC COMPANY (US) 1985-11-13 EP disclosed
EP-0067850-A4 BLENDS OF COPOLY (ESTER-CARBONATE) WITH POLYSULFONE. GEN ELECTRIC (US) 1983-04-18 EP disclosed
EP-0067850-A1 BLENDS OF COPOLY (ESTER-CARBONATE) WITH POLYSULFONE. GEN ELECTRIC (US) 1982-12-29 EP disclosed
US-4358569-A FLAME RESISTANT THERMOPLASTIC MOLDING MATERIAL OF GOOD IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1982-11-09 US disclosed
WO-1982002401-A1 BLENDS OF COPOLYESTER-CARBONATE WITH POLYSULFONE GEN ELECTRIC (US) 1982-07-22 WO disclosed
US-4175175-A POLYSULFONES, POLYSULFONAMIDES UNION CARBIDE CORPORATION (US) 1979-11-20 US disclosed
US-4108837-A THERMOPLASTIC, REACTING DIALKALI METAL SALT OF A DIHYDRIC PHENOL WITH A SUBSTITUTED DIHALOBENZENOID IN PRESENCE OF A SOLVENT UNION CARBIDE CORPORATION (US) 1978-08-22 US disclosed
US-4058607-A DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES AIRWICK INDUSTRIES, INC. (US) 1977-11-15 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030091859-A1 Fluorene compounds containing various functional groups, polymers thereof and el element using the same AFF4, AFF2, LEF1 SLC22A2 762/4885SLC22A1 738/4885SLC22A3 690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.