Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDXK | O00764 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12226964 | 0.85 | TP53 (0.38) | TDP1TP53TRPA1ALDH1A1ALOX5 | |
| SCHEMBL26048868 | 0.84 | TDP1 (0.41) | TDP1TP53TRPA1ALDH1A1PDXK | |
| SCHEMBL12802253 | 0.82 | TDP1 (0.42) | TDP1TP53TRPA1ALDH1A1ALOX5 | |
| SCHEMBL11928831 | 0.81 | ALDH1A1 (0.43) | TDP1TP53TRPA1ALDH1A1PDXK | |
| SCHEMBL10124488 | 0.80 | TP53 (0.41) | TDP1TP53TRPA1ALDH1A1ALOX5 | |
| SCHEMBL14709469 | 0.80 | ALDH1A1 (0.43) | TDP1ALDH1A1PTGS2 | |
| SCHEMBL29467225 | 0.80 | TP53 (0.41) | TDP1TP53TRPA1ALDH1A1ALOX5 | |
| SCHEMBL809833 | 0.80 | TP53 (0.41) | TDP1TP53TRPA1ALDH1A1ALOX5 | |
| SCHEMBL15524799 | 0.80 | TP53 (0.41) | TDP1TP53TRPA1ALDH1A1ALOX5 | |
| SCHEMBL16952356 | 0.78 | TP53 (0.39) | TDP1TP53TRPA1ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775230-A | Preparation method and application of tetrahydrofuran cyclostyrenes compound | 中国石油化工股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-7449493-B2 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMACEUTICAL COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-20050282882-A1 | Diamines as modulators of chemokine receptor activity | CARTER PERCY | 2005-12-22 | — | — | US | disclosed |
| US-6974836-B2 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-12-13 | — | — | US | disclosed |
| US-20030060459-A1 | Diamines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-03-27 | — | — | US | disclosed |
| US-4215175-A | Non-woven fibers coated with a polymer of ethylenically unsaturated blocked aromatic diisocyanates | THE B. F. GOODRICH COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4191833-A | BLOCKED WITH PYRAZOLE, ADDITION POLYMERS | THE B.F. GOODRICH COMPANY (US) | 1980-03-04 | — | — | US | disclosed |
| US-4191834-A | BLOCKED WITH BENZIMIDAZOLE, ADDITION POLYMERS | THE B.F. GOODRICH COMPANY (US) | 1980-03-04 | — | — | US | disclosed |
| US-4190582-A | Ethylenically unsaturated blocked aromatic diisocyanates | THE B. F. GOODRICH COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4189601-A | ADHESIVES, BINDERS FOR NONWOVEN FABRICS | THE B. F. GOODRICH COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4113958-A | POLYMERS USEFUL AS ADHESIVES AND BINDERS | THE B. F. GOODRICH COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4101491-A | USEFUL AS BINDERS FOR NONWOVEN FIBERS | THE B. F. GOODRICH COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4008247-A | POLYMER INTERMEDIATE | THE B. F. GOODRICH COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282882-A1 | Diamines as modulators of chemokine receptor activity | CCL11, CCR1, CCR2 | TDP1 1435/4885TP53 4856/4885TRPA1 480/4885 |
| US-20030060459-A1 | Diamines as modulators of chemokine receptor activity | CCL11, CCR1, CCR2 | TDP1 1296/4885TP53 4864/4885TRPA1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.