SCHEMBL5115161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5120140	0.87	P2RX4 (0.49)	P2RX4ALOX5MAPTALDH1A1SMN1; SMN2
	SCHEMBL3173450	0.86	TRPA1 (0.43)	P2RX4TRPA1ALOX5MAPTALDH1A1
	SCHEMBL5119452	0.86	CHRM4 (0.48)	MAPTALDH1A1SMN1; SMN2KDM4EMEN1
	SCHEMBL5507953	0.85	P2RX4 (0.46)	P2RX4TRPA1WDR5ALOX5MAPT
	SCHEMBL5125316	0.82	OPRD1 (0.45)	P2RX4HPGD
	SCHEMBL5118932	0.80	NPC1 (0.43)	P2RX4ALDH1A1SMN1; SMN2NPC1HPGD
	SCHEMBL5118934	0.80	NPC1 (0.43)	P2RX4ALDH1A1SMN1; SMN2NPC1HPGD
	SCHEMBL14051649	0.78	P2RX4 (0.45)	P2RX4ALDH1A1
	SCHEMBL14015224	0.77	P2RX4 (0.44)	P2RX4MAPTALDH1A1SMN1; SMN2HPGD
	SCHEMBL5503522	0.75	P2RX4 (0.46)	P2RX4MAPTSMN1; SMN2NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.