SCHEMBL5115741

SCHEMBL5115741

c1ccc(N(c2cccc(Oc3ccccn3)c2)c2cccc(Oc3ccccn3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.47
TLR2 O60603 1/20 0.47
GRM5 P41594 1/20 0.45
FFAR4 Q5NUL3 1/20 0.44
MAP4K4 O95819 1/20 0.42
IP6K1 Q92551 1/20 0.41
IP6K3 Q96PC2 1/20 0.41
IP6K2 Q9UHH9 1/20 0.41
KDM4E B2RXH2 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GPR39 O43194 1/20 0.40
LOXL2 Q9Y4K0 2/20 0.40
LOX P28300 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
PTGS2 P35354 2/20 0.38
DRD1 P21728 2/20 0.38
NPC1 O15118 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18903839 0.85 PTGS2 (0.47) TLR4TLR2GRM5IP6K1IP6K3
SCHEMBL17602146 0.84 TLR4 (0.48) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL12129555 0.82 TLR4 (0.56) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL29612417 0.82 TLR4 (0.56) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL30064803 0.82 TLR4 (0.35) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL15602369 0.81 TLR4 (0.55) TLR4TLR2GRM5FFAR4MAP4K4
SCHEMBL8943978 0.80 MAOB (0.48) KDM4ESMN1; SMN2L3MBTL1CYP1A2CYP2C9
SCHEMBL17602155 0.79 KDM4C (0.50) TLR4TLR2GRM5FFAR4IP6K1
SCHEMBL16890151 0.79 MAOB (0.47) KDM4ESMN1; SMN2L3MBTL1NPC1CYP1A2
SCHEMBL147539 0.78 LOXL2 (0.52) TLR4TLR2GRM5FFAR4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1683804-B1 PLATINUM COMPLEX AND LUMINESCENT ELEMENT TAKASAGO PERFUMERY CO LTD (JP) 2013-07-31 EP disclosed
EP-1683804-B1 PLATINUM COMPLEX AND LUMINESCENT ELEMENT TAKASAGO PERFUMERY CO LTD (JP) 2013-07-31 EP disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
EP-1683804-A2 PLATINUM COMPLEX AND LUMINESCENT ELEMENT Takasago International Corporation (JP) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070103060-A1 Platinum complex and light emitting device UBE2D3, PCID2, CCND2 TLR4 2268/4885TLR2 2277/4885GRM5 1971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.