SCHEMBL147539

SCHEMBL147539

c1ccc(Oc2ccccn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.52
LTA4H P09960 3/20 0.51
PTGS2 P35354 1/20 0.51
CYP1A2 P05177 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
GPR39 O43194 1/20 0.50
LOX P28300 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48
TLR4 O00206 1/20 0.47
TLR2 O60603 1/20 0.47
PDE10A Q9Y233 1/20 0.46
BLM P54132 2/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29610302 1.00 LOXL2 (0.52) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL8510667 0.98 LTA4H (0.50) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL5443693 0.98 LTA4H (0.50) LOXL2LTA4HPTGS2CYP1A2NPC1
Methyl Alcohol SCHEMBL11157137 0.96 GPR39 (0.51) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL11143982 0.93 PTGS2 (0.57) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL16345487 0.92 LTA4H (0.46) LOXL2LTA4HPTGS2CYP1A2NPC1
Formic Acid SCHEMBL27325993 0.88 TLR4 (0.48) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL7916927 0.88 KDM4E (0.46) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL9135525 0.87 KDM4E (0.56) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL28001241 0.87 LTA4H (0.50) LOXL2LTA4HPTGS2CYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1988 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735584-A Phenoxypyridine compound containing acylthiourea and heterocyclic structure, and preparation method and application thereof 东北农业大学 2025-04-01 CN claimed
CN-116710434-A Modulators of MAS-related G protein receptor X2 and related products and uses thereof 伊赛恩特制药公司 2023-09-05 CN claimed
EP-3898612-B1 SUBSTITUTED PYRIDINYLOXYBENZENES, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS BAYER AG (DE) 2023-08-02 EP claimed
EP-3898612-A1 SUBSTITUTED PYRIDINYLOXYBENZENES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS Bayer Aktiengesellschaft (DE) 2021-10-27 EP claimed
CN-110054589-B Synthetic method for synthesizing benzoquinoline ester derivative through heteroatom guiding 安徽师范大学 2021-09-28 CN claimed
CN-113302187-A Substituted pyridyloxybenzenes and their salts and their use as herbicides 拜耳公司 2021-08-24 CN claimed
CN-110746349-B Preparation method of m-difluoroalkylphenoxypyridine compound 安阳师范学院 2021-02-09 CN claimed
EP-3747868-A1 SUBSTITUTED PHENOXYPYRIDINES, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer AG (DE) 2020-12-09 EP claimed
CN-107011250-B Synthetic method and application of 2- (2, 6-dichlorophenoxy) pyridine compound 温州医科大学 2020-08-11 CN claimed
CN-107011251-B Synthesis method and application of 2- (2-chlorophenoxy) pyridine compound 温州医科大学 2020-08-11 CN claimed
US-4493730-A Phenoxypyridine useful as a herbicide ISHIHARA SANGYO KAISHA, LTD. (JP) 1985-01-15 US claimed
EP-0096354-A1 Substituted pyridyl-phenyl ethers BAYER AG (DE) 1983-12-21 EP claimed
US-4401460-A Herbicidal phenoxypyridines IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-30 US claimed
EP-0021613-B1 PYRIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM, HERBICIDAL COMPOSITIONS CONTAINING THEM AND METHODS OF KILLING PLANTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-06 EP claimed
EP-0029626-B1 WATER-BASED PESTICIDAL SUSPENSION AND PROCESS FOR ITS MANUFACTURE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-03-16 EP claimed
US-4308053-A PREEMERGENCE AND POSTEMERGENCE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-12-29 US claimed
EP-0041021-A2 Cyclopropane carboxylic acid derivatives, their preparation, their use against parasites in plants and animals, their compositions and their intermediates ROUSSEL-UCLAF (FR) 1981-12-02 EP claimed
US-4267336-A BY REACTING A 2-PHENOXYPYRIDINE DERIVATIVE WITH A 4-HYDROXYPHENOXYALKANECARBOXYLIC ACID DERIVATIVE ISHIHARA SANGYO KAISHA LTD. (JP) 1981-05-12 US claimed
US-4251662-A INSECTICIDES, MITICIDES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1981-02-17 US claimed
EP-0021613-A1 Pyridine derivatives, processes for preparing them, herbicidal compositions containing them and methods of killing plants therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-07 EP claimed