Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1772702 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL5013505 | 0.84 | ITGB3 (0.41) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL3405222 | 0.83 | CHRM1 (0.44) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL3980000 | 0.81 | SIGMAR1 (0.47) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL1840437 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL4929039 | 0.81 | HDAC3 (0.66) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL2211491 | 0.80 | — | — | |
| SCHEMBL1479904 | 0.79 | GNAI3 (0.50) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL19834800 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL193932 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468380-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-7109219-B2 | Nitrogen-containing aromatic derivatives | EISAI CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |
| EP-1522540-A1 | AZAARENE DERIVATIVES | Eisai Co., Ltd. (JP) | 2005-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | ITGB3 3808/4885ITGA2B 2817/4885HDAC3 496/4885 |
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | ITGB3 3808/4885ITGA2B 2817/4885HDAC3 496/4885 |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | ITGB3 3808/4885ITGA2B 2817/4885HDAC3 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.