Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 6/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117858 | 0.91 | NQO1 (0.46) | CSNK2A2CSNK2BCSNK2A1NQO1MCL1 | |
| SCHEMBL5341461 | 0.85 | NQO1 (0.39) | CSNK2A2CSNK2BCSNK2A1NQO1MCL1 | |
| SCHEMBL5115207 | 0.83 | NQO1 (0.47) | CSNK2A2CSNK2BCSNK2A1NQO1KDM4E | |
| SCHEMBL5126126 | 0.82 | NQO1 (0.48) | CSNK2A2CSNK2BCSNK2A1NQO1KMT2A | |
| SCHEMBL5118767 | 0.81 | HSD17B3 (0.37) | NQO1MCL1KDM4EGAAMAOB | |
| SCHEMBL5124909 | 0.81 | NQO1 (0.37) | NQO1KDM4EMAOBALDH1A1LMNA | |
| SCHEMBL5125229 | 0.81 | PRNP (0.42) | CSNK2A2CSNK2BCSNK2A1NQO1KMT2A | |
| SCHEMBL5125433 | 0.80 | NQO1 (0.38) | CSNK2A2CSNK2BCSNK2A1NQO1KMT2A | |
| SCHEMBL5120361 | 0.79 | NQO1 (0.53) | CSNK2A2CSNK2BCSNK2A1NQO1KMT2A | |
| SCHEMBL5120322 | 0.79 | NQO1 (0.46) | NQO1KMT2AKDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384975-B2 | Substituted furochromenes, preparation thereof and their antiinflammatory action | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2008-06-10 | — | — | US | disclosed |
| US-20060148889-A1 | Substituted furochromenes, preparation thereof and their antiinflammatory action | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2006-07-06 | — | — | US | disclosed |
| EP-1648902-A1 | SUBSTITUTED FUROCHROMENES, PREPARATION THEREOF AND THEIR ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005010007-A1 | SUBSTITUTED FUROCHROMENES, PREPARATION THEREOF AND THEIR ANTIINFLAMMATORY ACTION | PLIVA- ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148889-A1 | Substituted furochromenes, preparation thereof and their antiinflammatory action | CYP11B2, CYP11B1, LTC4S | CSNK2A2 886/4885CSNK2B 767/4885CSNK2A1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.