Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747039 | 0.85 | MEN1 (0.38) | HTTALDH1A1MMP13MEN1KMT2A | |
| SCHEMBL5112048 | 0.76 | MEN1 (0.41) | POLBHTTALDH1A1MMP13MEN1 | |
| SCHEMBL4748752 | 0.75 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1GRM2 | |
| SCHEMBL14033586 | 0.73 | HTT (0.35) | POLBHTTALDH1A1MMP13KMT2A | |
| SCHEMBL5114547 | 0.71 | MCHR1 (0.35) | SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5113909 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAL3MBTL1NCOA3POLB | |
| SCHEMBL3984185 | 0.71 | LMNA (0.40) | SMN1; SMN2LMNAL3MBTL1NCOA3POLB | |
| SCHEMBL3982263 | 0.68 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAL3MBTL1NCOA3POLB | |
| SCHEMBL3989708 | 0.68 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAL3MBTL1NCOA3POLB | |
| SCHEMBL3982232 | 0.68 | ALDH1A1 (0.38) | SMN1; SMN2LMNAL3MBTL1NCOA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332518-B2 | Carboxamides as fungicides in agriculture | SYNGENTA CROP PROTECTION, INC. (US) | 2008-02-19 | — | — | US | claimed |
| US-20040138265-A1 | Carboxamides as fungicides in agriculture | SYNGENTA CROP PROTECTION, INC. | 2004-07-15 | — | — | US | claimed |
| US-7435735-B2 | Hydroxy pyridopyrrolopyrazine dione compounds useful as HIV integrase inhibitors | MERCK & CO., INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7332518-B2 | Carboxamides as fungicides in agriculture | SYNGENTA CROP PROTECTION, INC. (US) | 2008-02-19 | — | — | US | disclosed |
| US-20070093496-A1 | Hydroxy pyridopyrrolopyrazine dione compounds useful as hiv integrase inhibitors | MERCK SHARP & DOHME CORP. | 2007-04-26 | — | — | US | disclosed |
| US-20040138265-A1 | Carboxamides as fungicides in agriculture | SYNGENTA CROP PROTECTION, INC. | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138265-A1 | Carboxamides as fungicides in agriculture | CBR3, CBR1, CNPY3 | SMN1; SMN2 4517/4885LMNA 2927/4885L3MBTL1 310/4885 |
| US-20070093496-A1 | Hydroxy pyridopyrrolopyrazine dione compounds useful as hiv integrase inhibitors | DHPS, DPYD, TYMP | SMN1; SMN2 3773/4885LMNA 2784/4885L3MBTL1 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.