Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 4/20 | 0.43 |
| ▸ | CASP7 | P55210 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.41 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5131574 | 0.98 | LMNA (0.49) | LMNAALDH1A1CASP3CASP7TSHR | |
| SCHEMBL3825000 | 0.94 | ALDH1A1 (0.45) | LMNAALDH1A1CASP3CASP7MEN1 | |
| SCHEMBL5121787 | 0.88 | ALDH1A1 (0.47) | LMNAALDH1A1MEN1KMT2AFKBP1A | |
| SCHEMBL5127710 | 0.86 | BRD4 (0.44) | ALDH1A1CASP3CASP7MEN1KMT2A | |
| SCHEMBL3823563 | 0.86 | ALDH1A1 (0.46) | LMNAALDH1A1CASP3CASP7MEN1 | |
| SCHEMBL3825150 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1CASP3CASP7MEN1 | |
| SCHEMBL5131871 | 0.86 | ALDH1A1 (0.45) | LMNAALDH1A1MEN1KMT2ANAMPT | |
| SCHEMBL3825618 | 0.86 | MEN1 (0.42) | LMNAALDH1A1MEN1KMT2AFKBP1A | |
| SCHEMBL5132569 | 0.85 | RECQL (0.44) | LMNAALDH1A1CASP3CASP7TSHR | |
| SCHEMBL5127744 | 0.85 | MEN1 (0.42) | LMNAALDH1A1CASP3CASP7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | claimed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | LMNA 1324/4885ALDH1A1 2737/4885CASP3 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.