Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | BRD2 | P25440 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5129990 | 0.87 | MEN1 (0.45) | MEN1KMT2AALDH1A1NAMPTCCR2 | |
| SCHEMBL5121906 | 0.86 | LMNA (0.47) | MEN1KMT2AALDH1A1NAMPTCASP3 | |
| SCHEMBL5128597 | 0.86 | BRD4 (0.46) | BRD4BRD2MEN1KMT2AALDH1A1 | |
| SCHEMBL3825000 | 0.85 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1NAMPTCASP3 | |
| SCHEMBL5131574 | 0.84 | LMNA (0.49) | MEN1KMT2AALDH1A1NAMPTCASP3 | |
| SCHEMBL5121787 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1NAMPT | |
| SCHEMBL5128465 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1NAMPT | |
| SCHEMBL3825150 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1NAMPTCASP3 | |
| SCHEMBL3809047 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1NAMPTCASP3 | |
| Hydrochloric Acid SCHEMBL5128006 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1NAMPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | BRD4 504/4885BRD2 808/4885MEN1 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.