SCHEMBL5122632

SCHEMBL5122632

N#CC=Cc1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.42
▸ STAT1 P42224 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8692255 0.80 STAT3 (0.43) STAT3STAT1
SCHEMBL352669 0.79 STAT3 (0.47) STAT3STAT1
SCHEMBL461738 0.79 STAT3 (0.47) STAT3STAT1
SCHEMBL7261521 0.79 STAT3 (0.42) STAT3STAT1
SCHEMBL8177649 0.76 STAT3 (0.50) STAT3STAT1
SCHEMBL1345645 0.76 STAT3 (0.49) STAT3STAT1
Water SCHEMBL4929925 0.75 STAT3 (0.58) STAT3STAT1
SCHEMBL1595495 0.75 STAT3 (0.44) STAT3STAT1
SCHEMBL3447556 0.75 STAT3 (0.44) STAT3STAT1
SCHEMBL1595493 0.75 STAT3 (0.44) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080280934-A1 Method of Preparing Porphyrin Derivatives, Porphyrin Derivatives, Uses Thereof and Pharmaceutical Compositions SPECTRACURE AB (SE) 2008-11-13 — — US claimed
EP-1709048-A2 METHOD OF PREPARING PORPHYRIN DERIVATIVES, PORPHYRIN DERIVATIVES, USES THEREOF AND PHARMACEUTICAL COMPOSITIONS Photobiochem N.V. (NL) 2006-10-11 — — EP claimed
WO-2005058909-A2 METHOD OF PREPARING PORPHYRIN DERIVATIVES, PORPHYRIN DERIVATIVES, USES THEREOF AND PHARMACEUTICAL COMPOSITIONS PHOTOBIOCHEM N.V. (NL) 2005-06-30 — — WO claimed
US-20080280934-A1 Method of Preparing Porphyrin Derivatives, Porphyrin Derivatives, Uses Thereof and Pharmaceutical Compositions SPECTRACURE AB (SE) 2008-11-13 — — US disclosed
EP-1709048-A2 METHOD OF PREPARING PORPHYRIN DERIVATIVES, PORPHYRIN DERIVATIVES, USES THEREOF AND PHARMACEUTICAL COMPOSITIONS Photobiochem N.V. (NL) 2006-10-11 — — EP disclosed
WO-2005058909-A2 METHOD OF PREPARING PORPHYRIN DERIVATIVES, PORPHYRIN DERIVATIVES, USES THEREOF AND PHARMACEUTICAL COMPOSITIONS PHOTOBIOCHEM N.V. (NL) 2005-06-30 — — WO disclosed
EP-0979104-B1 SONODYNAMIC THERAPY USING AN ULTRASOUND SENSITIZER COMPOUND AMERSHAM HEALTH AS (NO) 2004-09-15 — — EP disclosed
US-6498945-B1 FREE RADICAL GENERATION OF WATER SOLUBLE POLYMER TO ENHANCE CYTOPATHOGENIC EFFICACY AMERSHAM HEALTH AS (NO) 2002-12-24 — — US disclosed
EP-0979104-A1 SONODYNAMIC THERAPY USING AN ULTRASOUND SENSITIZER COMPOUND NYCOMED IMAGING A/S (NO) 2000-02-16 — — EP disclosed
WO-1998052609-A1 SONODYNAMIC THERAPY USING AN ULTRASOUND SENSITIZER COMPOUND NYCOMED IMAGING AS (NO) 1998-11-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280934-A1 Method of Preparing Porphyrin Derivatives, Porphyrin Derivatives, Uses Thereof and Pharmaceutical Compositions PANK2, PPOX, MVD STAT3 1825/4885STAT1 1862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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