SCHEMBL352669

SCHEMBL352669

O=Cc1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.47
▸ STAT1 P42224 1/20 0.47
▸ CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345645 0.97 STAT3 (0.49) STAT3STAT1CYP2A6
SCHEMBL1595493 0.95 STAT3 (0.44) STAT3STAT1CYP2A6
SCHEMBL1595495 0.95 STAT3 (0.44) STAT3STAT1CYP2A6
SCHEMBL9096665 0.89 STAT3 (0.47) STAT3STAT1CYP2A6
SCHEMBL6540939 0.88 STAT3 (0.39) STAT3STAT1
SCHEMBL8692255 0.86 STAT3 (0.43) STAT3STAT1
SCHEMBL461738 0.85 STAT3 (0.47) STAT3STAT1
SCHEMBL14012307 0.82 STAT3 (0.69) STAT3STAT1
SCHEMBL2752554 0.82 STAT3 (0.36) STAT3STAT1CYP2A6
SCHEMBL13573995 0.81 STAT3 (0.44) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103059033-A New method for preparing formyl-porphyrins UNIV NORTH CAROLINA STATE 2013-04-24 — — CN claimed
US-8420804-B2 Formyl- and acetal-porphyrins bearing tripodal linking groups NORTH CAROLINA STATE UNIVERSITY (US) 2013-04-16 — — US claimed
US-20110152515-A1 NEW ROUTE TO FORMYL-PORPHYRINS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-06-23 — — US claimed
US-20090137795-A1 NEW ROUTE TO FORMYL-PORPHYRINS NORTH CAROLINA STATE UNIVERSITY (US) 2009-05-28 — — US claimed
US-7501507-B2 Route to formyl-porphyrins NORTH CAROLINA STATE UNIVERSITY (US) 2009-03-10 — — US claimed
CN-101268080-A New way for preparing formyl porphyrin UNIV NORTH CAROLINA (US) 2008-09-17 — — CN claimed
US-20050277770-A1 condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-12-15 — — US claimed
EP-1353925-A2 PROCESSES FOR LARGE SCALE PRODUCTION OF TETRAPYRROLES Miravant Pharmaceuticals, Inc. (US) 2003-10-22 — — EP claimed
WO-2002083686-A2 PROCESSES FOR LARGE SCALE PRODUCTION OF TETRAPYRROLES MIRAVANT PHARMACEUTICALS, INC. (US) 2002-10-24 — — WO claimed
JP-7330773-A — — None — — JP disclosed
JP-3284681-A — — None — — JP disclosed
CN-119219645-B Preparation method of substituted diphenyl porphyrin-2-formaldehyde 湖南科技大学 2026-05-19 — — CN disclosed
CN-119219645-B Preparation method of substituted diphenyl porphyrin-2-formaldehyde 湖南科技大学 2026-05-19 — — CN disclosed
CN-119219645-A Preparation method of substituted diphenyl porphyrin-2-formaldehyde 湖南科技大学 2024-12-31 — — CN disclosed
US-20020137924-A1 Processes for large scale production of tetrapyrroles MIRAVANT PHARMACEUTICALS, INC. 2002-09-26 — — US disclosed
CN-1285832-A Synthesis of long-wavelength absorbing photosensitizers UNIV BRITISH COLUMBIA (CA) 2001-02-28 — — CN disclosed
US-6093739-A Synthesis of long wavelength absorbing photosensitizers THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2000-07-25 — — US disclosed
JP-H07330773-A PORPHYRIN DERIVATIVE AND ITS USE TOYO HATSUKA KOGYO KK 1995-12-19 — — JP disclosed
US-5252698-A Electrical conductors; liquid crystal polymers SRI INTERNATIONAL (US) 1993-10-12 — — US disclosed
JP-H03284681-A PORPHYRIN DERIVATIVE TOYO HATSUKA KOGYO KK 1991-12-16 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137795-A1 NEW ROUTE TO FORMYL-PORPHYRINS PPOX, DHPS, FDPS STAT3 3755/4885STAT1 3957/4885CYP2A6 759/4885
US-20020137924-A1 Processes for large scale production of tetrapyrroles SNU13, NPEPPS, ESYT2 STAT3 3763/4885STAT1 3066/4885CYP2A6 2823/4885
US-20110152515-A1 NEW ROUTE TO FORMYL-PORPHYRINS PPOX, ALAD, UROD STAT3 4123/4885STAT1 4328/4885CYP2A6 1340/4885
US-20050277770-A1 condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin DHPS, NOTUM, DOHH STAT3 4298/4885STAT1 4505/4885CYP2A6 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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