Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352669 | 0.97 | STAT3 (0.47) | STAT3STAT1CYP2A6 | |
| SCHEMBL1595493 | 0.95 | STAT3 (0.44) | STAT3STAT1CYP2A6 | |
| SCHEMBL1595495 | 0.95 | STAT3 (0.44) | STAT3STAT1CYP2A6 | |
| SCHEMBL9096665 | 0.89 | STAT3 (0.47) | STAT3STAT1CYP2A6 | |
| SCHEMBL6540939 | 0.87 | STAT3 (0.39) | STAT3STAT1 | |
| SCHEMBL14012307 | 0.85 | STAT3 (0.69) | STAT3STAT1 | |
| SCHEMBL8692255 | 0.83 | STAT3 (0.43) | STAT3STAT1 | |
| SCHEMBL461738 | 0.81 | STAT3 (0.47) | STAT3STAT1 | |
| SCHEMBL3447556 | 0.79 | STAT3 (0.44) | STAT3STAT1 | |
| SCHEMBL2752554 | 0.78 | STAT3 (0.36) | STAT3STAT1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103059033-A | New method for preparing formyl-porphyrins | UNIV NORTH CAROLINA STATE | 2013-04-24 | — | — | CN | claimed |
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | claimed |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-23 | — | — | US | claimed |
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-28 | — | — | US | claimed |
| US-7501507-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | claimed |
| CN-101268080-A | New way for preparing formyl porphyrin | UNIV NORTH CAROLINA (US) | 2008-09-17 | — | — | CN | claimed |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | claimed |
| CN-103059033-A | New method for preparing formyl-porphyrins | UNIV NORTH CAROLINA STATE | 2013-04-24 | — | — | CN | disclosed |
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | disclosed |
| US-8062756-B2 | Stepwise growth of oligomeric redox-active molecules on a surface without the use of protecting groups | The Regents oft the University of California (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-23 | — | — | US | disclosed |
| US-7919615-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-04-05 | — | — | US | disclosed |
| EP-1756115-A4 | A NEW ROUTE TO FORMYL-PORPHYRINS | UNIV NORTH CAROLINA STATE (US) | 2009-07-29 | — | — | EP | disclosed |
| US-7501507-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| CN-101268080-A | New way for preparing formyl porphyrin | UNIV NORTH CAROLINA (US) | 2008-09-17 | — | — | CN | disclosed |
| US-20070123618-A1 | Stepwise growth of oligomeric redox-active molecules on a surface without the use of protecting groups | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-05-31 | — | — | US | disclosed |
| WO-2007025114-A2 | STEPWISE GROWTH OF OLIGOMERIC REDOX-ACTIVE MOLECULES ON A SURFACE WITHOUT THE USE OF PROTECTING GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-03-01 | — | — | WO | disclosed |
| EP-1756115-A2 | A NEW ROUTE TO FORMYL-PORPHYRINS | North Carolina State University (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005123742-A2 | A NEW ROUTE TO FORMYL-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | PPOX, DHPS, FDPS | STAT3 3755/4885STAT1 3957/4885CYP2A6 759/4885 |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | PPOX, ALAD, UROD | STAT3 4123/4885STAT1 4328/4885CYP2A6 1340/4885 |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | DHPS, NOTUM, DOHH | STAT3 4298/4885STAT1 4505/4885CYP2A6 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.