Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127877 | 1.00 | MMP2 (0.74) | MMP2MMP9 | |
| SCHEMBL5131397 | 0.90 | MMP2 (0.74) | MMP2MMP9 | |
| SCHEMBL5131359 | 0.90 | MMP2 (0.74) | MMP2MMP9 | |
| SCHEMBL5131893 | 0.89 | MMP2 (0.74) | MMP2MMP9 | |
| SCHEMBL5126970 | 0.89 | MMP2 (0.74) | MMP2MMP9 | |
| SCHEMBL5131464 | 0.89 | MMP2 (0.74) | MMP2MMP9 | |
| SCHEMBL5126230 | 0.88 | MMP2 (0.76) | MMP2MMP9 | |
| SCHEMBL5127057 | 0.88 | MMP2 (0.75) | MMP2MMP9 | |
| SCHEMBL5130708 | 0.88 | MMP2 (0.75) | MMP2MMP9 | |
| SCHEMBL5131374 | 0.87 | MMP2 (0.76) | MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085893-A1 | MATRIX METALLOPROTEASE INHIBITORS | MMP3, MMP7, MMP9 | MMP2 5/4885MMP9 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.