Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761524 | 0.91 | LMNA (0.48) | TRPV1TRPA1SPHK1LMNATSHR | |
| SCHEMBL2530316 | 0.91 | TRPV1 (0.42) | TRPV1TRPA1SPHK1ALDH1A1TSHR | |
| SCHEMBL31501273 | 0.90 | TRPV1 (0.60) | TRPV1TRPA1SPHK1LMNATDP1 | |
| SCHEMBL620984 | 0.85 | ALDH1A1 (0.39) | TRPV1TRPA1SPHK1LMNAALDH1A1 | |
| SCHEMBL5186832 | 0.85 | ALDH1A1 (0.39) | TRPV1TRPA1SPHK1LMNAALDH1A1 | |
| SCHEMBL620986 | 0.85 | ALDH1A1 (0.39) | TRPV1TRPA1SPHK1LMNAALDH1A1 | |
| SCHEMBL620985 | 0.85 | ALDH1A1 (0.39) | TRPV1TRPA1SPHK1LMNAALDH1A1 | |
| SCHEMBL15423494 | 0.84 | TRPV1 (0.48) | TRPV1TRPA1SPHK1LMNACYP2D6 | |
| SCHEMBL109083 | 0.84 | — | — | |
| SCHEMBL8532467 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055964-A1 | METHOD FOR PRODUCING CYCLIC PHOSPHINES OR BIPHOSPHINES, CYCLIC PHOSPHONATES OF OPTICALLY ACTIVE DIOLS, AND THE PRODUCTION OF SAME | Rheinisch-Westfälische Technische Hochschule Aachen (DE) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008055963-A1 | NOVEL METHOD FOR PRODUCING ORGANIC PHOSPHORUS COMPOUNDS, PHOSPHORUS COMPOUNDS PRODUCED USING SAID METHOD, THE METAL COMPLEXES OF SAID COMPOUNDS, AND USE OF SAME | Rheinisch-Westfälische Technische Hochschule Aachen (DE) | 2008-05-15 | — | — | WO | disclosed |