Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 7/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5127968 | 0.92 | CNR1 (0.35) | ACACBTSHRTDP1DHODH | |
| SCHEMBL3338586 | 0.80 | ACHE (0.54) | ACHEAPPPDE4APDE4BPDE4C | |
| SCHEMBL3334990 | 0.80 | PIK3CD (0.50) | ACHEAPPPDE4APDE4BPDE4C | |
| SCHEMBL3334512 | 0.78 | ABL1 (0.42) | PDE4APDE4BPDE4CPDE4DPIK3CA | |
| SCHEMBL3341092 | 0.78 | ACHE (0.48) | ACHEAPPPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3334534 | 0.78 | DHODH (0.48) | ACHEAPPPIK3CAPIK3CGDHODH | |
| SCHEMBL5129286 | 0.78 | NPR1 (0.35) | RIPK1 | |
| SCHEMBL3335706 | 0.77 | NAMPT (0.42) | PIK3CADHODH | |
| SCHEMBL5129448 | 0.76 | JAK2 (0.43) | ACHEAPPTSHRTDP1 | |
| SCHEMBL3341513 | 0.74 | ACHE (0.48) | ACHEAPPPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009077-A2 | 4,6-DL- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | claimed |