Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 5/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 4/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132300 | 0.90 | CYP46A1 (0.40) | CYP46A1AVPR1ACYP2D6 | |
| SCHEMBL2566086 | 0.86 | BMP1 (0.42) | AVPR1B | |
| SCHEMBL5132545 | 0.84 | MEN1 (0.41) | AVPR1BCYP2D6CYP2C19HTR6 | |
| SCHEMBL5128437 | 0.84 | AVPR1A (0.43) | PKLRCYP46A1AVPR1A | |
| SCHEMBL5128035 | 0.84 | TP53 (0.41) | AVPR1BAVPR1AHTR6 | |
| SCHEMBL5131542 | 0.83 | TAS2R14 (0.47) | CYP46A1CYP2D6CYP2C19 | |
| SCHEMBL5122819 | 0.83 | OPRM1 (0.39) | PKLR | |
| SCHEMBL2569905 | 0.82 | BDKRB1 (0.48) | AVPR1BAVPR1AHTR6 | |
| SCHEMBL2562887 | 0.82 | BDKRB1 (0.48) | AVPR1BAVPR1AHTR6 | |
| SCHEMBL2565923 | 0.82 | BDKRB1 (0.50) | AVPR1BAVPR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | AVPR1B 14/4885PKLR 746/4885CYP46A1 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.