Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295249 | 0.82 | ALDH1A1 (0.42) | TSHRGAAMAPK1L3MBTL1KDM4E | |
| SCHEMBL11341214 | 0.82 | HPGD (0.36) | GAAKDM4ETDP1HPGDALDH1A1 | |
| SCHEMBL1404301 | 0.81 | MTNR1A (0.42) | TSHRGAAMAPTELANENPSR1 | |
| SCHEMBL9843253 | 0.81 | CA1 (0.39) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL181485 | 0.80 | THRB (0.40) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL7596823 | 0.79 | TSHR (0.50) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL12095456 | 0.78 | THRA (0.51) | PTGS2 | |
| SCHEMBL10879375 | 0.76 | TSHR (0.52) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL6392627 | 0.76 | MAPT (0.34) | MAPT | |
| SCHEMBL28090933 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210381-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | Alcon Universal, Ltd. (CH) | 2002-06-05 | — | — | EP | claimed |
| WO-2001018079-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON UNIVERSAL LTD. (CH) | 2001-03-15 | — | — | WO | claimed |
| US-9957343-B2 | Ionic bonding group-containing comb polymers | BYK-CHEMIE, GMBH (DE) | 2018-05-01 | — | — | US | disclosed |
| US-9556299-B2 | Surface-active comb copolymers | BYK-CHEMIE GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-20150203619-A1 | SURFACE-ACTIVE COMB COPOLYMERS | BYK-CHEMIE GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150152211-A1 | IONIC BONDING GROUP-CONTAINING COMB POLYMERS | BYK-CHEMIE GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| CN-103358742-A | Ink jet recording method, ultraviolet curable ink, and ink jet recording apparatus | SEIKO EPSON CORP | 2013-10-23 | — | — | CN | disclosed |
| US-20130018121-A1 | COMPOSITION COMPRISING STABLE POLYOL MIXTURES | BYK-CHEMIE GMBH (DE) | 2013-01-17 | — | — | US | disclosed |
| US-20120029104-A1 | COMPOSITION COMPRISING STABLE POLYOL MIXTURES | BYK-CHEMIE GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| EP-1210381-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | Alcon Universal, Ltd. (CH) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001018079-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON UNIVERSAL LTD. (CH) | 2001-03-15 | — | — | WO | disclosed |