Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132543 | 0.83 | SLC6A4 (0.40) | MTNR1AMTNR1BLPAR1 | |
| SCHEMBL5128416 | 0.78 | SLC6A4 (0.43) | MTNR1AMTNR1BKMT2ALPAR1ALDH1A1 | |
| SCHEMBL5665149 | 0.73 | CCR2 (0.56) | CCR2KDM4ECYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL3437042 | 0.69 | KDM4E (0.48) | HTTKDM4EHSD17B10CYP1A2KMT2A | |
| SCHEMBL31135570 | 0.69 | MTNR1A (0.56) | MTNR1AMTNR1BHTTKDM4ECYP1A2 | |
| SCHEMBL26102140 | 0.69 | MTNR1A (0.56) | MTNR1AMTNR1BHTTKDM4ECYP1A2 | |
| SCHEMBL28629032 | 0.67 | ALDH1A1 (0.47) | MTNR1AMTNR1BKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6471833 | 0.67 | MTNR1A (0.45) | MTNR1AMTNR1BHTTKDM4EHSD17B10 | |
| SCHEMBL27568865 | 0.67 | HTT (0.60) | CCR2HTTKDM4EHSD17B10CYP1A2 | |
| SCHEMBL28383724 | 0.66 | SERPINE1 (0.40) | CCR2HTTKDM4EMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183289-B2 | 4-substituted phenoxyphenylacetic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2012-05-22 | — | — | US | disclosed |