Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 10/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128573 | 0.92 | CCR1 (0.44) | CCR1ATMMEN1KMT2A | |
| SCHEMBL3825150 | 0.90 | ALDH1A1 (0.47) | CCR1ALDH1A1ATMMEN1KMT2A | |
| SCHEMBL5131509 | 0.90 | CCR1 (0.43) | CCR1ATMMEN1KMT2ACNR1 | |
| SCHEMBL5127990 | 0.89 | CHRM4 (0.41) | HSD11B1CHRM4MEN1KMT2A | |
| SCHEMBL5125564 | 0.89 | CHRM4 (0.45) | CHRM4MEN1KMT2A | |
| SCHEMBL5127118 | 0.88 | PKLR (0.42) | ALDH1A1ATMEPHX2 | |
| SCHEMBL5121787 | 0.88 | ALDH1A1 (0.47) | CCR1ALDH1A1ATMMEN1KMT2A | |
| SCHEMBL3827383 | 0.87 | CHRM4 (0.40) | HSD11B1CHRM4MEN1KMT2A | |
| SCHEMBL5127145 | 0.86 | OPRM1 (0.46) | CCR1 | |
| SCHEMBL5126195 | 0.86 | OPRL1 (0.45) | CHRM4MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | CCR1 598/4885HSD11B1 2319/4885CHRM4 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.