Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13374002 | 0.82 | MAPT (0.67) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5992360 | 0.82 | VCAM1 (0.60) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL2461199 | 0.80 | VCAM1 (0.58) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL20505550 | 0.79 | MAPT (0.68) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL2269212 | 0.78 | RAB9A (0.53) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL2245534 | 0.76 | HDAC6 (0.50) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14539000 | 0.74 | RAB9A (0.78) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL1897629 | 0.74 | CRHBP (0.58) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL1065964 | 0.74 | VCAM1 (0.51) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL5461467 | 0.74 | VCAM1 (0.57) | ALDH1A1MAPTMEN1KMT2AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986633-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit Corporation Plc (GB) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007091106-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2007-08-16 | — | — | WO | disclosed |