Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522896 | 0.69 | CASP1 (0.62) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5525346 | 0.69 | KCNA5 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5014910 | 0.68 | KDM4E (0.72) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL17872075 | 0.68 | CSF1R (0.54) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL8238647 | 0.67 | LMNA (0.80) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14917256 | 0.67 | ADORA2A (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6529865 | 0.67 | PDE10A (0.50) | KMT2AALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL6529863 | 0.67 | NCF1 (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3481335 | 0.67 | MAPT (0.51) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL5133306 | 0.67 | KDM4E (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937252-A2 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | Neuronascent, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007035722-A2 | METHODS AND COMPOSITIONS FOR STIMULATING NEUROGENESIS AND INHIBITING NEURONAL DEGENERATION | NEURONASCENT, INC. (US) | 2007-03-29 | — | — | WO | disclosed |